neurotransmitters Flashcards
NTS that can be both excitatory and inhibitory
Acetylcholine (ACh) and Substance P
Amino Acid NTs
Glutamate, aspartate, GABA, Glycine
Biogenic amines NTS (decarboxylated amino acids)
norepinephrine, epinephrine, dopamine, serotonin
ATP & other purines NTs
ATP, ADP, AMP
Large molecule NTs (neuropeptides)
Substance P
Small molecule NTs
Nitric oxide, carbon monoxide
The primary NT of the NMJ. Binds to excitatory ionotropic receptors at the NMJ, but can also bind to inhibitory metaboreceptors. IS broken down enzymatically by acetylcholinesterase
Acetylcholine
Excitatory amino acid NT. Specifically, it is eliminated from the synaptic cleft by reuptake mechanisms
Glutamate
Excitatory amino acid NT
Aspartate
Inhibitory amino acid NT. Tends to bind to ionotropic, hyperpolarizing receptors that activate Cl- channels
GABA/Glycine
Biogenic amine NT that is excitatory at the NMJ of cardiac and smooth muscle. Binds mostly to metabotropic receptors and is also a hormone
Norepinephrine
Biogenic amine NT that binds mostly to metabotropic receptors and is also a hormone
Epinephrine
Biogenic amine NTs of the CNS that are associated with a stunning range of function
Dopamine/Serotonin
Purine NTs that are excitatory NTs of the CNS and PNS
ATP/ADP/AMP
Neuropeptide NT that binds to metabotropic receptors to be either excitatory or inhibitory, depending on the type of ion channel. Involved in pain response
Substance P