Neurotransmitters Flashcards
Neurotransmitters
Chemical messenger released by neurones. Needs to pass a threshold. It is unidirectional meaning that it cannot happen the other way round
Excitatory Neurotransmitters
Neurotransmitters that increase the likelihood of a new action potential forming the postsynaptic cell. When detected by receptors in the postsynaptic cell, excitatory neurotransmitters make the electrical charge inside more positive and more likely to fire - Depolarisation. (Positively charged sodium ions Na+ enter the postsynaptic cell)
Inhibitory Neurotransmitters
Neurotransmitters that decrease the likelihood of a new action potential forming the postsynaptic cell, inhibitory neurotransmitters make the electrical charge inside more negative and less likely to fire - Hyper-polarisation. (Positively charged potassium ions K+ leave the postsynaptic cell)
Summation
The combined (summed) effect of all the excitatory and inhibitory neurotransmitter influences on the post synaptic neurone. If a threshold is reached, then a new action potential will form in the postsynaptic cell.
Agonists
increase the neurotransmitter effect (making the excitation or inhibition stronger)
Antagonists
reduce the effect of neurotransmitters (making the excitation or ignition weaker)
Neurotransmitters are
endogenous agonists - that is, they bind to and activate receptor sites on the post synaptic neuron.
Drugs are
exogenous agonists. They act in the same way, but they are not natural in our onerous system (eg: alcohol).