Neuroplasticity - SAQ Flashcards

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1
Q

Neuroplasticity

A

The ability of the brain to change through the making and breaking of synaptic connections between neurons.

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2
Q

The different scales of neuroplasticity

A

Synaptic plasticity

Cortical remapping

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3
Q

Synaptic plasticity

A

The ability of the neuron to form new synaptic connections and break up the old ones.

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4
Q

Cortical remapping

A

The phenomenon where a certain brain area assumes the functions of another brain area due injury for example.

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5
Q

How does synaptic plasticity work?

A

Depends on the activity of neurons.

If two nearby neurons are frequently activated at the same time, a synaptic connection between them may gradually form.

Similarly, if two neurons are rarely activated together, the existing connection may gradually fall apart.

When neurons fire continually as a result of stimulation in the environment, the neurons sprout new dendrites – known as dendritic branching.

This increases the number of synapses available for the behaviour.

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6
Q

Study used for neuroplasticity

A

Maguire

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7
Q

When was Maguire?

A

2000

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8
Q

Aim of Maguire (2000)

A

to see whether the brains of London taxi drivers would be somehow different as a result of their exceptional knowledge of the city and the many hours that they spend behind the wheel navigating the streets of London.

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9
Q

What was the sample?

A

16 right-handed male London taxi drivers.

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10
Q

How were the participants chosen?

A

Had to have completed the “Knowledge” test and have their license for at least 1.5 years

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11
Q

To who were the taxi drivers compared to?

A

50 right-handed males who did not drive taxis

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12
Q

How were they compared?

A

Compared using MRI scans

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13
Q

From where were the control participants taken from?

A

Were taken from an MRI database

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14
Q

What were the 2 different techniques used to analyse the MRI scans?

A

Voxel-based morphometry (VBM)

Pixel counting

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15
Q

Results from the pixel counting

A

The pixel counting showed that the posterior hippocampi of taxi drivers were significantly larger relative to those of control subjects and the anterior hippocampi were significantly smaller.

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16
Q

Results from the Voxel-based morphometry (VBM)

A

VBM showed that the volume of the right posterior hippocampi correlated with the amount of time spent as a taxi driver.

No differences were observed in other parts of the brain.

Maguire argues that this demonstrates that the hippocampus may change in response to environmental demands.

17
Q

Relation to neuroplasticity

A

By repeatedly firing the neurons required to remember the spatial layout of the city of London, the number of synapses was increased, creating a greater neural network

18
Q

What to know for neuroplasticity

A

Neuroplasticity
The different scales of neuroplasticity
Synaptic plasticity - how it works
Maguire (2000)

19
Q

Apoptosis

A

Neuronal cell death

20
Q

Long-term potentiation

A

The repeated firing of a neuron strengthens the connection.

In other words, neurons that fire together, wire together.

This is the biological explanation of why rehearsal leads to memory consolidation.

21
Q

Neurogenesis

A

The process by which new neurons are formed in the brain.

22
Q

Synaptic pruning

A

Also known as neuronal pruning, this is a natural process where the brain eliminates extra synapses.

Synaptic pruning is thought to be the brain’s way of removing connections that are no longer needed.