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Pharm Block 3 > Neuropsych > Flashcards

Neuropsych Flashcards

1
Q

Amitriptyline

A

Tricyclic antidepressant
Block NE and 5-HT reuptake
Decrease REM
Chronic pain

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2
Q

Clomipramine

A

Tricyclic antidepressant
Block NE and 5-HT reuptake
Decrease REM
OCD

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3
Q

Fluoxetine

A

SSRI

long half life

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4
Q

Sertraline

A

SSRI

short half life

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5
Q

Bupropion

A

Blocks NorEpi and Dopamine reuptake

tx- nicotine withdrawal

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6
Q

Mirtazapine

A

block alpha2 receptors

increase appetite

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7
Q

Duloxetine

A

SNRI
block 5HT and NorEpi reuptake
caution with patient with liver disease

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8
Q

Phenelzine

A

irreversible MAO inhibitor

blocks breakdown of 5-HT

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9
Q

Chlorpromazine

A

Phenothiazines
Low potency
sedative
anticholinergic

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10
Q

Clozapine

A

effects neg symptoms, weight gain

agranulozytosis

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11
Q

Thioridazine

A

low potency
sedative
anticholinergic

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12
Q

Fluphenazine

A

high potency
less sedative and less anticholinergic
more extrapyramidal

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13
Q

Haloperidol

A

similar to Fluphenazine

high potency

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14
Q

Olanzapine

A

5-HT 2 antagonist

weight gain

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15
Q

Risperidone

A

DA and 5-HT antagonist

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16
Q

Quetiapine

A

Effects D2 and 5-HT2

17
Q

Aripiprazole

A

D2 partial agonist

18
Q

Lithium

A

Depletes recycling of IP2 to PIP. Thus decreasing pathway
Narrow therapeutic window
Side effects- fatigue, tremor, GI, caution in pregnant, slurred speech, ataxia

19
Q

Valproic Acid

A 
Anti-Seizure
Block repetitive firing
reduce T-Ca current
increase GABA
Side effect- GI upset, weight gain, Hair loss
Teratogen-Spinal Bifida
20
Q

Divalproex

A 
Anti-Seizure
Block repetitive firing
reduce T-Ca current
increase GABA
Side effect- GI upset, weight gain, Hair loss
Teratogen-Spinal Bifida
21
Q

Carbamazepine

A

Blocks Na channels
does not affect GABA
Teratogen- Spinal Bifida

22
Q

Alprazolam

A

Benzodiazepine
Anti-anxiety
Panic Disorder

23
Q

Buspirone

A

5HT and D2 agonist

takes 1-2 weeks

24
Q

Chloral Hydrate

A

hypnotic

25
Q

Diazepam

A

Benzodiazepine
Anti-anxiety
muscle relazation
IV-sedation and anestesia

26
Q

Flumazenil

A

BLOCKS Benzodiazepine

27
Q

Flurazepam

A

Benzodiazepine

Anti-anxiety

28
Q

Lorazepam

A

No active metabolites

29
Q

Pentobarbital

A

Hypnotic

30
Q

Zolpidem

A

binds to Benzodiazepine receptor

anti anxiety

31
Q

Baclofen

A

GABA receptor
muscle relaxant
antianxiety

32
Q

Tizanidine

A

alpha2 agonist

sympathetic inhibition

Pharm Block 3 (10 decks)

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