CNS Stimulant Flashcards
1
Q
Caffine
A
Stimulant
Blocks adenosine
Inhibit phosphodiesterase (incrased cAMP) benifit for asthma
release of Ca stores
2
Q
Adenosine
A
produce IPSP
inhibit glutamate release
(depressant)
3
Q
Methylphenidate
A
releases NE, DA and 5-HT
Longer action than Cocaine
elevate mood and wakefulness
4
Q
Cocaine
A
inhibitor of NE, 5-HT and DA reuptake
weak base
the free base is lipid soluble and volatile
test for urine metabolites
5
Q
Amphetamine
A
releases NE, DA and 5-HT Longer action than Cocaine elevate mood and wakefulness tx- narcolepsy, ADHD Side effect- weight loss, insomnia
6
Q
Methamphetamine
A
releases NE, DA and 5-HT Longer action than Cocaine elevate mood and wakefulness Better CNS availibility Side effect- weight loss, insomnia Tx- ADHD
7
Q
Nicotine
A
nicotinic receptors in Autonomic ganglia
Lung to brain in 7 seconds
8
Q
Bupropion
A
reduces nicotine withdrawal
9
Q
Varenicline
A
partial nicotinic agonist
reduces withdrawal
