Neurophysiology 2: Mental Control, Sensory System, Higher Cortical Functions Flashcards
What are the 3 kinds of memory?
- short-term
- long term
- working memory
Where are short term memories stored at?
Hippocampus
What are the 2 types of long term memory?
Explicit and Implicit
What are explicit long term memories?
you need to think to retrieve information
What are implicit long term memories?
you don’t need to think to retrieve information
What are the 2 kinds of explicit memory? Where are they processed?
- Semantic: Facts
- Episodic: Events
- medial temporal lobe
- hippocampus
What are the 4 kinds of implicit memory?
- priming:
- exposure to a stimulus influences response to a subsequent stimulus unconsciously
- procedural:
- “knowing how” to do something
- associative:
- connection is made between 2 stimuli or between a stimuli and behavior
- non-associative:
- doesn’t require assoc. between 2 stimuli
What is the general flow of memory?
- central executive
- prefrontal cortex
- short-term
- hippocampus
- long-term
- neocortex
Where is long term memory formed?
neocortex
What are the 2 types of amnesia?
- Retrograde: loss of memory before concussion
- Anterograde: loss of memory after concussion (cannot form new memory)
What are changes in the synapse called?
plasticity
The number of neurons of a person cannot be changed, how then do people become smarter?
neurons form connections w/ each other. It can be strengthened or weakened
What are the forms of plastic change?
- post-tetanic potentiation
- Habituation
- Sensitization
- Long Term Potentiation
- Long Term Depression
What is the phenomenon where there is a temporary increase in synaptic strength following a high-frequency burst of action potentials, in which postsynaptic potential increases via the accumulation of calcium?
posttetanic potentiation
What is a non-associative form of learning in which a neutral stimulus is repeated many times?
Habituation
What is sensitization?
- form of non-associative learning
- organism becomes more responsive to a stimulus after being exposed to a strong or noxious stimulus
- increased responsiveness.
Where does calcium accumulate in long-term potentiation?
post-synaptic neuron
Where does calcium accumulate at posttetanic potentiation?
pre-synaptic neuron
In long term depression, where does learning occur?
cerebellum
What is long term depression characterized by?
- reduction in efficiency of synaptic transmission
- synaptic connections are weakened/eliminated
- removing old/irrelevant information
Where does memory transfer occur?
anterior portion of the corpus callosum
What are the structures involved in memory?
- Hippocampus and Parahippocampus around Medial Temporal Lobe
- HC, diencephalon and thalamus
- Amygdala
- Neocortex
Conditioned reflexes pass through which structures to be transferred to contralateral side?
- optic chiasm
- posterior and anterior commissure
What happens during the bilateral destruction of the ventral hippocampus?
Short-term memory defects
Removing the medial temporal lobe is a common intervention for people with epilepsy, why?
- Medial temporal lobe is the common site for seizures
- dominant side is spared as this is associated with memory
What part of the brain is responsible for encoding emotionally charged memories?
amygdala
Which region of the brain is responsible for the production of speech?
Broca’s area
Which region of the brain is responsible for the understanding of speech?
Wernicke’s Area
What is agnosia?
can’t understand meaning
What is apraxia?
can’t execute voluntary motor functions despite intact motor, sensory, and mental status pathways.
What is Agraphesthesia?
inability to recognize letter/numbers traced on skin. Impairment in tactile perception + somatosensory processing
What is aphasia?
can’t understand or express words despite pathways to receive and express language is intact
Give 7 diseases related to agnosia.
- Agraphesthesia
- Prosopagnosia
- Asomatognosia
- Left Side Hemispatial Inattention
- Anosognosia
- Inattention to double simultaneous cutaneous stimuli
- Gertsmann
What is prosopagnosia?
inability to recognize faces. located at inferomedial temporo-occipital region
A patient comes in with a lesion of the right parietal lobe. What test can be done to determine what kind of agnosia he acquired?
Draw a clock.
Px likely has left side hemispatial inattention.
You ask your patient to point to their right index finger. However, they point at the left thumb. Which part of the brain is damaged and what kind of agnosia does he have?
Left Angular Gyrus. Asomatognosia.
Finger agnosia is commonly seen in what syndrome?
Gertsmann Syndrome
Give 5 kinds of apraxia.
- face tongue apraxia
- ideomotor apraxia (language dom. hemisphere)
- Constructional Apraxia
- Dressing Apraxia
- Gait Apraxia
What are the 4 levels of disturbed speech production?
- Dysphonia - larynx
- Dysarthria - articulating sounds
- Dysprosody - can’t control volume/melody of speech
- Dysphasia - cortex
What is the BA 22?
Wernicke’s
What are the 2 types of aphasia?
- Receptive (sensory aphasia)
- Expressive (motor aphasia)
What is BA 39?
Angular gyrus
What is BA 17?
Primary visual cortex
What part of the brain is responsible for speaking?
Broca’s area
What part of the brain is responsible for reading or figures of words?
angular gyrus
What connects the Wernicke’s to Broca’s?
Posterior parasylvian
A patient can understand what people are saying and even form responses in their brain, however unable to communicate it. Which region of the brain is likely damaged?
posterior parasylvian
What part of the brain is responsible to converting figures into words?
angular gyrus
A patient comes in talkative however cannot understand. What kind of aphasia does he have?
Wernicke’s
A patient comes in with good speech and understanding, however cannot repeat. What kind of aphasia does he have?
Conduction
A patient comes in with damage at the entire parasylvian area. What kind of aphasia does he have and what symptomps should you expect?
can’t talk, understand, or repeat
Classify the somatosensory system by order.
- central
- peripheral
What makes up the peripheral sensory nervous system?
- Sensory receptor
- Sensory axon
- Spinal nerve
- Dorsal root ganglion
- Dorsal root
What fibers sense pain and temperature?
A-delta & C fibers (small fiber)
What fibers sense vibration and position sense?
A-alpha & A-beta fiber (large fiber)
In the CNS sensory system, what tract is responsible for pain and temperature?
spinothalamic tract
Where does the dorsal column tract decussate?
medulla
In the CNS sensory system, what tract is responsible for vibration and position sense?
dorsal column tract
Where does the spinothalamic tract decussate?
spinal cord
The left thumb feels pain. Where is its associated spinothalamic tract at?
contralateral (i.e. right) side of spinal cord
My right arm is feeling vibrations. Where is its associated dorsal column tract located?
Ipsilateral (right) side of medulla.