Neuropath Intro Flashcards
what is the pink background of gray matter called?
neuropil
what cell is high density in white matter of brain?
oligodendrocytes
name two cells in white matter of brain
oligodendrocytes and astrocytes
what is a stain used to see astrocytes?
GFAP
how do astrocytes and oligodendrocytes appear in a GFAP stain?
astrocytes brown and oligo with halo
what is stain used to see axons in white matter?
silver stain
what is stain used to see myelin around axons?
luxol fast blue stain
how do leptomeninges usually appear on specimen of brain
clear and translucent
what does the arachnoid layer look like on histo slide?
pink area with lots of cells collected
what does the pia mater look like on histo slide?
small thin layer
axonal injury leads to distal degeneration how quickly?
within 24 hours
2-3 days after axonal injury what cell type is there?
microglia
what do microglia do in axon injury site?
phagocytosis of degenerating myelin etc
what cell proliferates around the microglia in an axon injury?
astrocytes
what happens to astrocytes at axon injury over the next few weeks?
get hypertrophied and then lose the hypetrophy and lead to fiber filled astrocytes