Clinical Stroke Info Flashcards
name 5 common cardiac causes of emboli strokes
a fib prosthetic valves MI endocarditis cardiomyopathy
what are two most common associations with lacunar infarcts?
diabetes and HTN
name a heme disorder that can lead to cerebral infarction?
sickle cell disease
what is time frame for TIA?
10 minutes to 4hours
what can you NOT have in TIA?
any infarction
what are TIA patients at high risk for?
stroke duh
what are vision changes seen in carotid ischemi?
transient monocular blindness ipsilateral
what is motor change seen in caroti ischemia?
contralateral weakness and numbness of hand, arm, face
can you have language deficit in carotid ischemia?
yes…if dominant hemi
what are vision changes in vertebrobasilar ischemia?
dipoplia (double vision)
binocular graying/ loss of vision
what is motor change invertebrobasilar ischemia?
unilateral or bilateral weakness/numbness in limbs
what is cranial nerve change in vertebrobasilar ischemia?
dysphagia
what is balance change in vertebrobasilar ischemia?
lack of balance…vertigo and staggering
what is the clinical syndrome of lacunar infarcts to know?
pure motor lacunar infarct
where does the pure motor lacunar infarct affect?
the internal capsule
what portions of body are affected by pure motor lacunar infarct?
face arm and leg ipsilaterally
what is a non contrast CT sensitive for?
hemorrhage is best seen with non contrast CT
what drug given for acute stroke?
IV alteplase
what is mechanism of alteplase?
binds fibrin and converst plasminogen into plasmin and plasmin then goes to break up clot
what is SE with alteplase?
bleeding
when should you never give IV alteplase?
if it is a hemorrhagic stroke!!
if you cant do alteplase, what can you do to remove stroke clot?
thrombectomy
what two drugs do we give for secondary stroke prevention?
aspirin and clopidogrel
how long do patients take aspirin and clopidogrel?
21-90 days post event
after 90 days of aspirin and clopidogrel, what do we switch to for stroke prevention?
warfarin or DOACs
what are the DOACs for stroke prevention?
apixaban (Xa inhib)
rivaroxaban (Xa inhib)
dabigatran (direct thrombin inhib)
edoxaban (Xa inhib)
