Neuronal Damage And Recovery Flashcards

0
Q

If we end up with too many disconnected, unused cells floating around, we disrupt the

A

Efficiency, connectivity, and speed of the entire system

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1
Q

By what week in utero have we usually developed all requires nerve cells we will ever have

A

25th

But we have produced more than we need

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2
Q

Apoptosis

A

Programmed death as much of 50% of cells that aren’t well-connected or we already have a redundant connection
Intentional death of cell body itself

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3
Q

Synaptic pruning

A

Need to refine and support only efficient, necessary networks
Pruning away atonal connections that are not competitive, stimulated, used, or needed

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4
Q

Apoptosis is programmed “clean”

A

Phagocytosis is executed without any explosive, leaky, mess

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5
Q

Necrosis

A

Is messy unwanted phagocytosis, has a big mess on its hands

Tbi, cut off oxygen or blood

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6
Q

Spinal cord trauma

A

Bending, tearing, cutting, dislocation, hyperextension, hypereflexion
Damage depends on level if SC injury, degree of injury

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7
Q

Spinal cord injury- disease

Occlusion

A

Occlusion of arteries needed to supply neurons in the spinal cord
Anterior spinal artery occlusion due to atherosclerotic disease

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8
Q

Degeneration of neurons in the spinal cord

A

Amyotrophic lateral sclerosis- ALS

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9
Q

ALS

A

Progressive degeneration if lateral corticospinal tracts
Loss of anterior horn cells throughout sc and bs
Muscle atrophy, paresis, death
Spinal cord synapse are no longer available for motor control

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10
Q

Spinal cord disease

A

Tumor

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11
Q

Spinal cord disease inflammation

A

Transverse myelitis
Progressive inflammation and attack on myelin at one level of the sc
Better hope of recovery for this

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12
Q

Spinal cord injury

A

Unnatural movement of axons

Depending where damage is/how far extend into spinal cord- motor or sensory

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