Damage/diaordes Of Myelin

Question 0

Direction of conductivity can be tracked using diffuser tensor imaging (DTI)

Answer 0

Allows us to see the degree of myelin

Allows us to observe the directional flow if information through tracts and nerves

Question 1

The crucial element for neuronal communication

Answer 1

Myelin
Speed of conductivity (50% faster in myelinated axons)
Via nodes of ranvier

Question 2

Damage, disease to: white matter tracts/fibers cns
Or
Spinal nerve and cranial nerves pns

Answer 2

Causes a loss of conductivity, which disrupts neuronal communication
Tracts (& nerves) NEED myelin to messages

Question 3

Diffuse axonal injury

Answer 3

Sustained in tbi
Twisting, shearing, of the myelin and/ or axon itself
Cytoskeleton of axon becomes misaligned, swells, and then becomes incapable if conveying an impulse
Eventually disconnects and is done

Question 4

DAI dame he tracts throughout the brain

Answer 4

Corona radiati 
Internal capsule
Association tracts
Corpus callosum
Can result in death, coma, or severe cognitive disorders

Question 5

Demyelinating diseases

Answer 5

Loss of integrity/presence of myelin
Axon cannot transmit as quickly or at all
If there is no us of this nerve and it’s connects it’s pruned away and discarded

Question 6

Examples if autoimmune:inflammatory demyelinating diseases

Answer 6

Multiple sclerosis
Guilian barre
Encephalitis

Question 7

Multiple sclerosis

Answer 7

Caused by autoimmune inflammatory response
Deterioration of myelin and replaced with plaque within cns
Atrophy of the corpus callosum, white matter near or around ventricles, SC

Question 8

Gillian Barre

Answer 8

Autoimmune attach of myelin system of peripheral nerves

Rapid onset, may be fatal, long recovery

Question 9

Encephalitis

Answer 9

HIV - complex related; following childhood diseases

Question 10

Myelin disorders- white matter ischemia

Answer 10

Peripheral arteriolar more susceptible to ischemic events- blockages, narrowing
White matter may become deprived of sufficient blood supply- oxygen
Occurs most frequently I’m subcortical white mater tracts