neuromuscular structure and function Flashcards

1
Q

what is the function of the cerebral cortex

A
  • language
  • reasoning and abstract thinking
  • sensory and voluntary motor control
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2
Q

what is the function of the basal ganglia

A
  • initiation and execution of movements
  • facilitate desired movements and inhibit unwanted competing movements
    (chooses actions that are likely to lead to positive consequences)
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3
Q

what is the function of the hypothalamus

A
  • metabolism and temp
  • autonomic NS (cardiovascular and cardiorespiratory rhythm)
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4
Q

what is the function of the limbic system

A
  • processing and interpretation of sensory info
  • controls motivation and goal directed behaviour influencing the initiation and maintenance of exercise routines
  • promotes adaptive reactions to physical challenges and aids in the management of stress related hormones
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5
Q

what does the limbic system release and what is the function

A
  • release of endorphins that contribute to the feelings of pleasure and euphoria (runners high)
  • leads to improved mood and reduced perception of pain during PA (exercise induced hypoalgesia - pain reduction)
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6
Q

what is the function of the brainstem

A
  • passage connects motor and sensory neurons to the spinal cord
  • contain nuclei that regulate the cardiac and respiratory functions
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7
Q

what is reduced vagal tone from brainstem

A

increased sympathetic nerve activation therefore increased HR and ventilation

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8
Q

what is the function of the cerebellum

A
  • processes the info necessary to regulate body posture and equilibrium (balance)
  • receives sensory info form sensory afferents
  • sends info to thalamus and than cerebral cortex
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9
Q

what is the corticospinal tract

A

collection of axonal nerves bundles (white matter) initiating at the cerebral cortex, passing through the brainstem and terminating on lower MNs

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10
Q

what occurs at the pyramidal decussation

A

90% decussate - lateral CST controls extremities
10% don’t decussate - ventral CST controls trunk and core muscles

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11
Q

how many pairs of spinal MNs are there

A

31

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12
Q

what is the pathway of a spinal cord reflex

A
  1. stimulus
  2. afferent pathway
  3. monosynaptic connection (afferent neuron connects directly to efferent neuron)
  4. efferent pathway
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13
Q

how long does a spinal cord reflex take

A

<150 ms
- doesn’t go all the way to the brain

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14
Q

what is a MU made up of

A

an aMN and the specific muscle fibres that it innervates
- makes up the functional unit of mvmt

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15
Q

what is the difference in ratios between small and large MUs (aMN:muscle fibres)

A

small = 1:5 - fine mvmt
large = 1:800 - gross mvmt

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16
Q

what are the 3 stages of an AP

A
  1. depolarisation (influx of Na+)
  2. repolarisation (outflux of K+)
  3. ions return back with Na+/K+ pumps
17
Q

what does the speed of conduction depend on

A

unmyelinated vs myelinated
(nociceptors = unmyelinated)
- saltatory conduction on myelinated nerves

18
Q

what occurs when an AP reaches the NM junction

A
  1. presynaptic terminal - AP reaches and releases ACh
  2. ACh travels across the synaptic cleft
  3. postsynaptic terminal - AP generates here due to ACh receptors
  4. synaptic vesicles contain ACh
  5. AP goes to t-tubule and touches sarcoplasmic reticulum causing Ca2+ release
19
Q

what is the function of the spinal reflex

A

used for anything related to maintaining balance quickly
- skating, running on unstable surfaces, etc

20
Q

what is the all or none principle

A

all muscle fibres innervated in a MU are stimulated to contract

21
Q

what is the size principle

A

anatomic basis for the orderly recruitment of small to large MUs to produce a smooth muscle action

22
Q

what is recruitment

A

increasing the number of MUs recruited
- occurs first

23
Q

what is rate coding

A

increasing frequency of MUs discharge
- occurs second

24
Q

what is the order of recruitment and rate coding during exercise

A

both increase as exercise intensity increases
- recruitment = first
- rate coding = second

25
what are muscle spindles
fusiform structure embedded in the muscle - monosynaptic - no interneuron
26
what do muscle spindles respond to
any stretch of the muscle - provides mechnosensitive info about changes in muscle fibre lngth and tension - sends info to spinal cord and sends excitatory info back to the aMNs
27
what do nuclear bag fibres respond to
phasic stretch (changes in stretch)
28
what do nuclear chain fibres respond to
static stretch (maintained stretch)
29
where are GTOs
in the muscle tendon unit
30
what are GTOs
responds to the tenison created by muscle contraction (active force production NOT stretching) - protective sensory mechanism
31
what do GTOs do
reduces the level of muscle contraction and tension in the muscle - has an inhibitory interneuron that inhibits the aMN during dangerously high active force production (main difference from muscle spindle)
32
what is the stretch (myotatic) reflex
involuntary contractions of muscle from a rapid stretch - only involves afferent and efferent neurons and 1 synapse - spinal cord only
33
what is the function of the stretch reflex
helps the body to maintain its balance in a fraction of a second - tiny adjustments all the time to keep standing