Neurological Viruses Flashcards

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1
Q

What type of vaccine is safer?

A

Killed vaccine

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2
Q

What type of vaccine is more effective?

A

Live attenuated

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3
Q

Arhtropod transmission vectors

A

Mosquitoes, ticks

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4
Q

Reservoirs for arthropod transmission

A

Birds and small mammals

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5
Q

EEE and VEE Biology

A

Togaviridae
Genome: +ssRNA
Virion: enveloped
Proteins: E1 and E2, Capsid, Various non-structural proteins

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6
Q

EEE and VEE introduced by what?

A

Bite of an infected arthropod

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7
Q

EEE and VEE body transmission

A

Langerhans cells, replication through blood stream, can infect other organs such as CNS

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8
Q

Incubation period for EEE and VEE

A

4-10 days, short

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9
Q

Systemic Symptoms of EEE and VEE

A

Chills, fever, malaise, arthralgia, myalgia for 2 weeks

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10
Q

Prevention and control of EEE and VEE

A

A single vaccine is available-TC-83

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11
Q

Encephalatic symptoms of EEE and VEE

A

Death after 2-10 days, long term seizures, personality disorders, paralysis

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12
Q

Treatment for EEE and VEE

A

No treatment, just control mosquitoes

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13
Q

EEE and VEE are more prevalent where in the US?

A

Southern/eastern humid places

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14
Q

West Nile Virus Incubation time

A

2-14 days, short

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15
Q

Symptoms of WNV

A

Asymptomatic, or fever, headache, fatigue for 3-6 days

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16
Q

Treatment and prevention of West Nile

A

No treatment other than supportive care, No vaccine

17
Q

West Nile virus locations in US

A

Basically everywhere

18
Q

Why does west nile virus present across more of the US than EEE and VEE?

A

Mosquitoes that carry WNV have a larger broader habitat

19
Q

Rabies biology

A

Rhabdoviridae
Genome: -ssRNA
Virion Enveloped
Proteins: N, P, M, G, L

20
Q

Rabies needs what?

A

RNA Polymerase

21
Q

Rabies are transmitted by what?

A

By bite of infected animal

22
Q

Rabies incubation period

A

moderate/long 1-3 months

23
Q

Symptoms of Rabies

A

Itching where bitten, Hydrophobia-foaming at the mouth, Cerebral dysfunction

24
Q

Treatment/Prevention of rabies

A

Vaccine available, post exposure prophylaxis (4 doses)