Hepatitis Virus

Question 1

Does Hep A have chronic infections?

Answer 1

Nope

Question 2

Which Hepatitis viruses have chronic problems associated with it?

Answer 2

Hep B and C

Question 3

Hep B Biology

Answer 3

Hepadnaviridae
Genome: dsDNS
Virion: Enveloped
Proteins: HBsAg-s, m, l,HBcAg, Pol

Question 4

Heb B has what that is important?

Answer 4

Reverse transcriptase

Question 5

Hep B has to be grown in what?

Answer 5

Liver cells

Question 6

Can Hep B infect organs other than liver?

Answer 6

No

Question 7

Hep B causes a lot of what which are used for what?

Answer 7

Empty capsids, Diagnosis

Question 8

Routes for Hep B

Answer 8

Sexual or drug abuse

Question 9

Hep B has a ____ incubation period? (long, short, or moderate)

Answer 9

Long

Question 10

Jaundice is a symptom of what?

Answer 10

Liver problems/Hep B

Question 11

Chronic disease of Hep B occurs in ~ __% of people?

Answer 11

5%

Question 12

Is there a vaccine available for Hep B?

Answer 12

Yes

Question 13

Treatment for Chronic infections of Hep B

Answer 13

Interferon-a therapy, adefovir, lamivudine, tenofovir

Question 14

Hepatitis D encodes how many proteins?

Answer 14

1. Hep D isn’t super important. Only 1 slide in his presentation.

Question 15

Hepatitis C biology

Answer 15

Flaviviridae
Genome: +ssRNA
Virion: enveloped
Proteins: E1, E2, C, Various non-structual

Question 16

Hep C genome is passed into what part of the cell?

Answer 16

Cytoplasm

Question 17

Symptoms of Hep C

Answer 17

Milder symptoms but much more likely to have Chronic infections.

Question 18

Hep C can move to tissues other than Liver. T/F

Answer 18

True

Question 19

Treatment for Hep C

Answer 19

Zepatier- No vaccine available

Question 20

Hep A is infected how?

Answer 20

Fecal to oral

Question 21

Incubation period for Hep A

Answer 21

15-40 days- Moderate

Question 22

Symptoms of Hep A

Answer 22

Maliase, anorexia, vomiting, jaundice

Question 23

Prevention/treatment for Hep A

Answer 23

Vaccine

Question 24

Hep E virus is similar to which other Hep?

Answer 24

Hep A

Question 25

Prevention/treatment of Hep E

Answer 25

No vaccines

Question 26

Hep C virus incubation period

Answer 26

Long- 60-120 days