Herpes Flashcards
Characteristics of Herpes virus
Variable host range
Short reproductive cycle
Rapid spread
Destroy infected cells
Herpes 1 is where on the body?
Waist up
Herpes 2 is where on the body”
Waist down
AlphaHerpes primarily infect what type of cells?
Epithelial cells
Incubation period for alphaherpes
2-14 days
What can trigger alphaherpes?
Stress, sunburn, infection…
Prevention of alphaherpes
Avoid contact during active herpes recurrence
Treatment for alphaherpes
Acyclovir- limits the breakouts
Betaherpesvirus example
Cytomegalovirus (CMV)
Characteristics of Betaherpes
Restricted host range
Slow in replication
Enlargement of infected cells
Gammaherpes characcteristics
restricted host range
Target T and B lymphocytes
Epstein-Barr Virus (EBV or Mono)
EBV can cause what?
Burkett’s lymphoma-cancer in children, jaw or eye socket or ovaries
EBV Carcinomas
Hodgkins lymphoma
3 types of Hodgkins lymphoma
NL-nodular sclerosing
MC-mixed cellularity
LD-lymphocyte depleted
Why does EBV cause certain cancers?
People don’t really know
3 ways the virus tries to avoid the immune system
Intrinsic-Stopping cell death
Innate-Inhibit natural killer cells
Adaptive-Prevent expression of things antibodies can recognize
Treatment for Beta/gamma herpes
Self limiting or can do antiviral therapy for immune compromises individuals
Human Papillomavirus biology
Papillomaviridae
Genome: Circular dsDNA
Virion-Non-enveloped
Proteins: L1, L2
HPV gains access how?
Through abrasion of the skin-Needs differentiation of skin cell layers
