Neurobiology Flashcards
what makes up the CNS?
brain and spinal cord
what makes up the peripheral nervous system?
somatic (sensory info and signals from CNS to muscles) and autonomic (regulates internal environment)
whats the difference between parasympathetic and sympathetic nervous system?
para - generally calming
sympathetic - generally arousing
what makes up the forebrain?
basal ganglia, cerebral hemisphere, diencephalon
what makes up the midbrain and hindbrain?
brain stem which is made up of midbrain, pons, medulla oblongata
hindbrain makes it all up and also includes the spinal cord and cerebellum
what makes up a neuron?
cell body/soma, dendrites, axon, axon hillcock, axon terminal
function of cell body and axon?
cell body - integrates input and converts to output
axon - conducts output signal and terminal transmits the output
what are microglia?
small mesodermally derived, defensive function - immune cells of the CNS - can become macrophages
what are astroglia?
star shaped, symmetrical, nutritive and support function
support neurons by physically separating cells
- regulating K conc
- remove neurotransmitters after they’ve been realised by neurons
- release growth factors
what’s the potential of the inside of the cell?
-50 - 70mV (inside more negative than outside)
whats the action potential graph like?
steady then curves up to overshoot (+40mV)
dips to the undershoot (-70mV)
raises again to resting potential (-65mV)
what’s the action potential?
sodium/potassium pump action - it propagates down the axon
why can’t the action potential go backwards?
due to the absolute refractory period - recovery time
why is mylein important?
insulates to prevent leakage of ions - help action potentials travel faster
what’s synaptic transmission?
action potentials depolarise the axon terminal causing the fusion of vesicles to the plasma membrane and release of neurotransmitters
what are the two types of receptors?
ionotropic - ligand gated
metabotropic - g-protein receptors
how do excitatory transmitters work?
activate receptors that allow sodium influx driving towards action potential