Neurobiology Flashcards
Regulates respiration, heart rate, blood pressure
medulla
Regulates sleep-wake cycles
pons
Regulates reflexes and balance. Coordinates movement
cerebellum
Major sensory relay center. Regulates higher brain centers and peripheral nervous system
Thalamus
Area of the brain involved with emotion and motivation. Stress reactions
Hypothalamus
Area of the brain involved with formation of new memories
hippocampus
Governs emotions related to self-preservation
amygdala
Result of prolonged exposure to a neurotransmitter
down-regulation of receptors
Result of prolonged lack of stimulation of a receptor
up-regulation of receptors
Degeneration of this tract results in the motor symptoms of Parkinson’s disease. Absence of D2 receptor activity results in bradykinesia. Is a dopaminergic tract
Nigrostriatal tract
Is a dopaminergic tract. May be involved in mediating the antipsychotic effects of antipsychotic drugs
Mesolimbic-mesocortical tract
ventral tegmental area –> most areas of cerebral cortex and limbic system
Mesolimbic-mesocortical tract
substantia nigra–>corpus striatum
Nigrostriatal tract
arcuate nucleus–>infundibulum & anterior pituitary
Tuberoinfundibular tract
acts as a release inhibiting factor with regards to prolactin
dopamine
Possible side effect of dopamine antagonists?
elevated prolactin levels and galactorrhea
common adverse effect of giving a medication that antagonizes the effects of dopamine
tremors
abused drug that causes the release of dopamine
amphetamines
street drug that inhibits uptake of dopamine
cocaine
is what stimulates release of dopamine and glutamate in tobacco products
nicotine
Result of low levels of serotonin
depression
Result of high levels of serotonin
mania
Patient populations that are also helped by SSRIs in addition to depression
schizophrenia and anxiety
commonly associated with Alzheimer’s dementia as well as other dementias
acetylcholine
can impair learning and memory in normal people
anticholinergic agents
a newer generation antipsychotic. dopamine and serotonin antagonist as opposed to only a dopamine antagonist
Seroquel (Quetiapine)
Characterized by fatigue, dizziness, and nausea after abruptly stopping an SSRI prescription
serotonin withdrawal syndrome