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Psych > Depression and Treatment > Flashcards

Depression and Treatment Flashcards

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1
Q

what aspect of depression do these sx address: depresed mood, anhedonia, decreased interest, irritability, guilt/worthlessness, suicidal ideation

A

psychological

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2
Q

what aspect of depression do these sx address: appetite, sleep, energy, concentration

A

neurovegative

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3
Q

What does SIGECAPS stand for?

A

sleep, interest, guilt, energy, concentration, appetite, psychomotor, suicidal

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4
Q

Frequency of depressive symptoms that qualifies it as a disorder

A

symptoms occur in the same two weeks, most of the day and nearly everyday

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5
Q

Risk factors include: family h/o, childhood onset of depression, no response or agitation to antidepressants

A

bipolar disorder

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6
Q

sx include: euphoria, irritability, grandiosity, increased energy, decreased sleep, risk taking, more talkative

A

bipolar disorder

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7
Q

Type of bipolar characterized by mania that lasts one week and marked impairment

A

bipolar disorder I

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8
Q

Type of bipolar characterized by hypomania that lasts 4 days and there is a change that is observable by others

A

bipolar disorder II

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9
Q

Psychotic features

A

delusions, hallucinations, disordered thought

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10
Q

What do the following conditions have in common: sleep apnea, hypothyroidism, chronic pain, stroke, heart disease

A

medical conditions that can cause depression

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11
Q

Name some common medication classes that can cause depression

A

beta-blockers, corticosteroids, benzodiazepine, Varenicline (Chantix)

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12
Q

Comorbid psychiatric conditions with depression

A

anxiety disorders and substance abuse

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13
Q

What does DIGFAST stand for?

A

distractible, impulsive, grandiose, flight of ideas, activities, sleep, talkative

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14
Q

What does CAGE stand for?

A

felt need to Cut down on drinking, annoyed by ppl criticizing your drinking, felt Guilty about your drinking, ever had an Eye opener

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15
Q

Hamilton anxiety score that indicates significant anxiety

A

> 20

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16
Q

Name the SSRIs

A

Fluvoxamine (Luvox), Paroxetine (Paxil), Sertraline (Zoloft), Citalopram (Celexa), Escitalopram (Lexapro), Fluoxetine (Prozac)

17
Q

First line treatment of depressive disorders. No real differences in efficacy. Difference in side effects and half lives

A

SSRIs

18
Q

Side effects include: GI disturbance, sexual dsyfxn, anxiety, insomnia/sedation, sweating, dizziness

A

SSRIs

19
Q

Acts on both serotonin and norepinephrine. Not clearly more efficacious

A

SNRIs

20
Q

Name the two SNRIs

A

Venlafaxine (Effexor). Duloxetine (Cymbalta)

21
Q

Indicated for neuropathy

A

Duloxetine (Cymbalta)

22
Q

Side effects of SNRIs

A

HTN and tachycardia

23
Q

Name the TCAs

A

Amitriptyline, Nortriptyline, Clomipramine, Doxepin, Imipramine

24
Q

Side effects include: Anticholinergic, Antihistamine, Orthostatic hypotension, Cardiac

A

TCAs

25
Q

Why are TCAs not frequently used?

A

lethal in overdose and more drug-drug interactions

26
Q

Name the two MAOIs

A

phenelzine (Nardil), tranylcypromine (Parnate)

27
Q

Good for sleep at low doses. If tolerated – functions as an AD at higher doses. Watch for sedation, orthostasis, priapism

A

Trazodone

28
Q

Uses include: Major Depressive disorder: ADHD: Smoking cessation

A

Bupropion

29
Q

CI to Bupropion

A

seizure disorders and bulimia

30
Q

Antidepressant that is safe in pregnancy and can be added on to SSRI to restore libido

A

Bupropion

31
Q

Used off-label for insomnia

and as appetite stimulant. Good for patients with nausea

A

Mirtazapine

32
Q

How long does it take at a minimum for medication to be effective?

A

2-4 weeks

33
Q

What should you do if there is no improvement in patient in 4-6 weeks?

A

consider switch, increase dose or augmentation

34
Q

Most expensive antidepressant

A

Duloxetine

35
Q

Population with increased risk of suicide with antidepressants

A

up to 24yrs old

36
Q

Longer acting benzos with lower abuse potential. Short term use

A

clonazepam, lorazepam over alprazolam, diazepam

Psych (20 decks)

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