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FA - Neurology > Neuro3 > Flashcards

Neuro3 Flashcards

Neurotransmitters BBB Hypothalamus

1
Q

Where in the brain is NE synthesized?

A

Locus ceruleus (pons)

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2
Q

Where in the brain is Dopamine synthesized?

A

Ventral tegmentum & SNc (midbrain)

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3
Q

Where in the brain is 5-HT synthesized?

A

Raphe nucleu (pons)

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4
Q

Where in the brain is ACh synthesized?

A

Basal nucleus of Meynert

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5
Q

Where in the brain is GABA synthesized?

A

Nucleus accumbens

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6
Q

What NT is INcreased in anxiety?

A

NE

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7
Q

What NTs are DEcreased in depression?

A

NE, Dopamine, 5-HT

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8
Q

What NTs are are decreased in Huntington’s?

A

ACh, GABA

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9
Q

What NTs are DEcreased in anxiety?

A

5-HT, GABA

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10
Q

What NT is INcreased in REM sleep?

A

ACh

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11
Q

What emotional states are associated with the Locus ceruleus?

A

Stress & Panic

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12
Q

Reward center, pleasure, addiction, and fear are associated with what regions of the brain?

A

Nucleus accumbens & Septal nucleus

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13
Q

What 3 structures form the BBB?

A

Tight junctions
Basement membrane
Astrocyte foot processes

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14
Q

What brain regions have no BBB?

A

Area prostrema - vomiting after chemo

OVLT - osmotic sensing

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15
Q

What is the mnemonic regarding the Hypothalamus?

A

“TAN HATS”

Thirst
Adenohypophysis control (regulates A. Pit.)
Neurohypophysis releases hypth hormones
Hunger
Autonomic regulation
Temperature regulation
Sexual urges
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16
Q

Where is ADH produced?

A

Supraoptic nucleus

17
Q

Where is Oxytocin produced?

A

Paraventricular nucleus

18
Q

What are the 5 regions of the hypothalamus?

A 
Lateral area
Ventromedial area
Anterior hypothalamus
Posterior hypothalamus
Suprachiasmatic nucleus
19
Q

Functional roles of hypothalamus region:

Lateral area

A

Hunger

  • Inhibited by Leptin
  • Destroyed in anorexia

“if you shrink your LATERAL nucleus, you shrink LATERALLY”

20
Q

Functional roles of hypothalamus region:

Ventromedial area

A

Satiety

  • Stimulated by leptin
  • Destruction = hyperphagia (craniopharyngioma)

“if you zap your VENTROMEDIAL nucleus, you grow VENTRALly & MEDIALly”

21
Q

Functional roles of hypothalamus region:

Anterior Hypothalamus

A

Cooling, PARAsympathetic

“A/C = Anterior Cooling

22
Q

Functional roles of hypothalamus region:

Posterior Hypothalamus

A

Heating, SYMpathetic

“if you zap your Posterior Hypothalamus, you become a Poikilotherm (cold-blooded)

23
Q

Functional roles of hypothalamus region:

Suprachiasmatic nucleus

A

Circadian Rhythm

“you need SLEEP to be CHARISMATIC”

FA - Neurology (22 decks)

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