neuro extras Flashcards
frontotemporal dementia investig
MRI - shows atrophy
frontotemporal dementia symptoms
degenerative
memory loss, personality changes
frontal - behavioural emotional
temporal - language impair, aphasia
frontotemporal dementia treatment
no cure
symp alleviation - antidepressants antipsychotics
frontotemporal dementia cause/rf
clumps of abnormal protein forming inside brain cells
fam hist only known rf
vascular dementia cause/rf
vasculitis, multiple cerebrovascular events, chronic ischaemia = reduce blood supply to brain
smoking, chronic hpn, diabetes, hyperlipidaemia
vascular dementia investig
CT/MRI
vascular dementia pres
progressive stepwise cognitive function impair
can improve a bit and then get worse again
vascular dementia treatment
antihypertensive drugs
lifestyle
lewy body dementia treatment
acetylcholinesterase inhibitor
dopamine analogue for parkinsonian symp
lewy body dementia pres
psychotic - hallucinations later stages of parkinsons degenerative 50-85 yrs more rapid decline than alzheimers
alzheimers investig
CT (Mini–Mental State Examination)
alzheimers treatment
acetylcholinesterase inhib
vit E
aducanumab - reduces amyloid plaque
alzheimers pres and common aspects mnemonic
-inability to remember new info
executive dysfunction
behavioural/psych at later stage
Reduction of Ach Old age Neurofibrillary tangles Atrophy of cerebral cortex Language impairment Down's syndrome
alzheimers RF
old age
family hist
trisomy 21 (downs)