Neuro Dr Vidhya Flashcards

1
Q

Headache: Cluster or Migrainous Neuralgia CLINICAL FEATURES

A

TRIAD:
* Retroorbital Headache
* Rhinorrhoea
* Lacrimation

Unilateral headache

Occurs nightly or in the early hours of
the morning

No visual disturbances or vomiting

Hallmark : Cyclical nature of the attacks and at least 5 attacks. Occurs typically in males; Rare in childhood.

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2
Q

Headache: Cluster or Migrainous Neuralgia ACUTE Management

A

1st line: 100% O2 15 L/min for 15 minutes

2nd line: Sumatriptan sc injection or intranasally

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3
Q

Headache: Cluster or Migrainous Neuralgia PROPHYLAXIS (once a cluster starts TO PREVENT FURTHER ATTACKS)

A
  1. For control of attack – Naratriptan
  2. Methysergide
  3. Prednisolone
  4. Lithium
  5. Verapamil
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4
Q

Headache: Tensional Clinical findings

A

Symmetrical bilateral tightness (muscle contraction headaches)

Lasts from 30 minutes to 7 days

Non-pulsating, mild to moderate intensity

No nausea, vomiting, photophobia, or phonophobia

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5
Q

Headache: Tensional Management

A

Relaxation techniques

Lifestyle modifications

Avoid tranquilisers and stronger analgesics

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6
Q

Headache: Tensional Treatment

A
  1. CBT
  2. Mild non-opioid analgesics – aspirin, ibuprofen, paracetamol
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7
Q

Headache: Migraine Clinical Features

A

MC triggered by Stress

Headache lasts 4- 72 “hours”

Unilateral, Pulsatile in nature.

Moderate or severe intensity, inhibiting daily activities associated with nausea, vomiting, photophobia, or phonophobia

Not attributable to another disorder

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8
Q

Headache: MILD
Acute Migraine Management

A

1st line: ASPIRIN OR
PARACETAMOL + METOCLOPRAMIDE

ADVISE LYING DOWN
IN A QUIET DARK COOL ROOM.

COLD PACKS ON THE FOREHEAD OR NECK.

AVOID: COFFEE, TEA, MOVING AROUND TOO MUCH, READING, WATCHING TV

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9
Q

Headache: SEVERE
Acute Migraine Management

A

1st line: TRIPTANS (BEST AT START OF ATTACK)

AVOID IN:

  • CORONARY ARTERY
  • DISEASE
  • ANGINA
  • UNCONTROLLED HYPERTENSION
  • PREGNANCY
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10
Q

Management of Acute Migraine attack during pregnancy

A

Paracetamol is the preferred non-opioid analgesic.

Avoid NSAIDs and
Aspirin in the first trimester and after 30 weeks of gestation

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11
Q

Management of severe refractory Acute Migraine attack during pregnancy

A
  • IV fluids
  • Short course of IV
  • MgSO4 or oral steroids.

NOTE: Beta blockers can cause IUGR and should be weaned off before labour to prevent Fetal bradycardia.

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12
Q

Migraine Prophylaxis

A

1st line: Avoidance of known trigger factors.

Indication: 2 or more
severe migraine attacks per month attacks disrupting the
patient’s well being/lifestyle.

Drugs:
* Beta blockers (Propranolol)
* TCA (Amitryptyline)
* Sodium valproate
* CCBs ( Verapamil, Nifedipine)
* Candesartan
* Sumatriptan
* Gabapentin
* Botulinum toxin into the muscles of the face, scalp or neck

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13
Q

Headache: Temporal
arteritis (Giant cell arteritis) CLINICAL FEATURES

A

Persistent/intermittent unilateral throbbing headache in the
temporal region and scalp sensitivity with localized thickening

With or without loss of pulsation of the Superficial temporal artery.

Age > 50 years

Intermittent blurred vision

Tenderness on brushing hair

Jaw claudication on eating

Hypertension

Polymyalgia Rheumatica

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14
Q

Headache: Temporal
arteritis (Giant cell arteritis) MANAGEMENT

A

1) Very responsive to corticosteroids- start treatment immediately to prevent permanent blindness.

2) Aspirin to prevent ischemic events

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15
Q

Headache: Subarachnoid Hemorrhage CLINICAL FEATURES

A

Presentation: Acute severe headache “thunderclap” (in 75% patients); Loss of consciousness in the remaining 25%.

TRIAD
* Occipital Headache
* Vomiting
* Neck stiffness

Also:
- With or without seizures
- Kernig sign positive

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16
Q

Headache: Subarachnoid Hemorrhage INVESTIGATIONS

A

Dx: 1) CT Head – investigation of
choice

2) Lumbar puncture is used if CT scan is
negative – Homogenous blood staining of CSF
and Xanthochromia are diagnostic of SAH

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17
Q

Headache: Subarachnoid Hemorrhage CT Imagen

A

Areas of hyper density within the cisterns and sulci

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18
Q

Headache: Subarachnoid Hemorrhage Management

A

URGENT REFERRAL!!

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19
Q

Headache: Trigeminal
Neuralgia CLINICAL FEATURES

A

> 50 yo

Almost always unilateral

Presentation:
* Brief paroxysms of pain 1-2 minutes (upto 15 minutes)
* Excruciating burning knife or electric shock like pain.
* Precipitated by talking, chewing, touching trigger areas on face, cold weather, and wind.

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20
Q

Headache: Trigeminal
Neuralgia. Associated diseases

A
  • Multiple sclerosis
  • Neurosyphilis
  • Posterior fossa Tumours
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21
Q

Headache: Trigeminal
Neuralgia Investigation

A

MRI

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22
Q

Headache: Trigeminal
Neuralgia MANAGEMENT

A

1st line: Patient education and reassurance.

2nd line: Carbamazepine (from onset of attack until resolution)

3rd line: Surgery. Just if medical treatment is ineffective: Decompression of the Trigeminal nerve root

23
Q

CLINICAL FEATURES Idiopathic Intracranial Hypertension (Pseudotumour cerebri)

A
  • Obese young patient
  • Headache
  • Nausea
  • Visual obscuration or blurring (main concern
    from high ICP) check papilledema.
24
Q

FIRST INVESTIGATION Idiopathic Intracranial Hypertension (Pseudotumour cerebri)

A

CT and MRI are normal.

25
BEST INVESTIGATION Idiopathic Intracranial Hypertension (Pseudotumour cerebri)
Lumbar puncture: Increased CSF pressure 25 cm H2O with Normal CSF analysis.
26
MANAGEMENT Idiopathic Intracranial Hypertension (Pseudotumour cerebri)
1st: URGENT REFERRAL!! 2nd: * Stop causative drugs * Weight reduction * Corticosteroids and diuretics NOTE: Choice to alleviate symptoms: Repeated Lumbar Puncture
27
Medication overuse Headache CLINICAL FEATURES
BILATERAL “Headache all day everyday”
28
Medication overuse Headache CAUSE
NSAIDs, triptans, ergotamine. Typically with regular use > 15 days per month for 3 months
29
Medication overuse Headache Treatment
Gradual withdrawal of the drugs; Bridging therapy with a short course of steroids or NSAID
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GCS
31
MANAGEMENT of Coma of unknown cause in the ED
TONG(F) or Coma cocktail
32
Transient Ischemic Attack (TIA) CLINICAL FEATURES
* Short duration (< 60 minutes) * Consciousness preserved * Complete clinical recovery in < 24 hours (spontaneous)
33
Carotid TIAs CLINICAL FEATURES
90% ischemic attack in anterior circulation (Carotid) Unilateral features: * Amaurosis fugax * Dysphasia * Unilateral weakness, paralysis or numbness of face and arm (especially) and leg.
34
Vertebrobasilar TIAs CLINICAL FEATURES
Bilateral or crossed features: * Homonymous hemianopia * Bilateral blurring of vision, blindness, or diplopia * Vertigo * Nausea ± vomiting * Dysarthria * Hemiplegia * Ataxia ± bilateral weakness or numbness, drop attacks.
35
TIA INVESTIGATIONS
1. CT or MRI 2. Carotid duplex Doppler NOTE: Also ECG but depends on the question
36
TIA MEDICAL MANAGEMENT
FIRST: Aspirin or (Clopidogrel + Aspirin) or (Dipyridamole + Aspirin) or Ticlopidine NOTE: Dual therapy within 24 hours and cease at three weeks. If failed antiplatelet therapy or vertebrabasilar ischemia: WARFARIN DOACs for non-valvular, AF >65 yo
37
TIA SURGICAL MANAGEMENT
Based on the Carotid duplex Doppler Results (CDUS): Symptomatic (Ipsilateral TIA or Stroke) – 70-99%: Intervention – 50-69%: Grey area- REFER! – <50%: Observe Asymptomatic: > 80%: Non-urgent intervention < 80%: Annual survillance with CDUS Surgery: **Carotid Endarderectomy**
38
STROKES TERRITORIES. Anterior Circulation Arteries
1. Anterior Cerebral Artery 2. Middle Cerebral Artery 3. Lenticulo-striate Artery
39
STROKES TERRITORIES. Posterior Circulation Arteries
1. Posterior Cerebral Artery 2. Basilar Artery 3. Anterior inferior cerebellar artery 4. Posterior inferior cerebellar artery 5. Anterior spinal artery
40
Anterior Cerebral Artery Stroke CLINICAL FEATURES
41
Middle Cerebral Artery Stroke CLINICAL FEATURES
42
Lenticulo-striate Artery Stroke CLINICAL FEATURES
43
Posterior Cerebral Artery Stroke CLINICAL FEATURES
44
Basilar Artery Stroke CLINICAL FEATURES
45
Anterior inferior cerebellar artery Stroke CLINICAL FEATURES
**Lateral Pontine Syndrome** - *General* (VII Nerve Nuclei) ↓ Lacrimation ↓ Salivation ↓ Taste anterior 2/3 of the tongue (Vestibular nuclei) Vomiting Vertigo Nystagmus - *Contralateral* BODY↓ Pain and temperature sensation - *Ipsilateral* FACE ↓ Pain and temperature sensation Horner syndrome Ataxia Dysmetria (Inner ear) Sensorineural deafness
46
Posterior inferior cerebellar artery Stroke CLINICAL FEATURES
**Lateral Medullary (Wallenberg) Syndrome** (IX, X, XI Nerves Nucleus) **Dysphagia Hoarseness** Dysphonia ↓ Gag reflex Hiccups Vomiting Vertigo Diplopia Nystagmus (horizontal and vertical) - *Contralateral* BODY↓ Pain and temperature sensation - *Ipsilateral* FACE ↓ Pain and temperature sensation Horner syndrome Limb Ataxia Dysmetria
47
Anterior spinal artery Stroke CLINICAL FEATURES
**Medial Medullary Syndrome**
48
Lacunar Infartcts Types
1. Pure motor (contralateral) 2. Pure sensory (contralateral) 3. Ataxic hemiparesis 4. Dysarthria-Clumsy hand Syndrome
49
Dominant side- Parietal Lobe Lesion
**Gerstmann’s Syndrome** Tetrad 1. dysgraphia 2. dyscalculia 3. finger agnosia (can't touch the fingers together) 4. Left to right disorientation ALSO: Aphasia, dysphasia Alexia, dyslexia
50
Non dominant Parietal lobe lesion
* Geographical agnosia * Phonagnosia (difficulty in recognizing familiar voices) * Amusia * Constructional Apraxia * Asomatognosia * Anosognosia * Spatial neglect * Neglect of contralateral limb * Dressing apraxia
51
Vertigo
* Peripheral * Central
52
Cause for periperal Vertigo
* Labyrinth ( Meniere, Labyrintitis, BPPV, drugs/trauma, CSOM) * Eight cranial nerve ( Vestibular neuronitis, acustic Neurinoma, drugs) * Cervical
53