Nerve Impulse Flashcards
How are nerve impulse generated
Changes in concentrations of ions inside and outside nerve cell causing a potential difference (PD), called action potential
Trasmite an electrical signal between nerve cells
How are action potentials reached
If threshold potential not reached, nothing happens
A new action potential cannot be generated in same section of membrane for about 5milliseconds. Makes sur impulse travels in 1 direction along nerve fibres
What is depolarisation
Refers to sudden change in membrane potential from relatively negative to positive internal charge
Process of depolarisation
During it:
- Voltage gated sodium ion channels open due to an electrical stimulus
- As Na+ rushes back into cell, the Na+ diffuse into cell raising the charge from neg to pov
If threshold potential not reached, nothing happens
Process of repolarisation
Once cell depolarised, voltage gated sodium ion channels close
Repol is when:
- Raised positive charge inside cell causes potassium channels to open. K+ ions move down their electrochemical gradient, diffusing out of cell
- As K+ diffuses out of cell, membrane potential falls and starts to approach resting potential
K+ gates close
Recovery
Resting potential equilibrium restored
K+ moves back into cell through non-voltage gated channels
Repol typically overshoots resting membrane potential, making membrane potential more negative. Known as hyper polarisation
Saltatory Condution
Only region of myelinated nerve fibre that can depolarise at node of Ranvier where there is no myelin. Means nerve impulse can travel much longer distance
Can also travel faster than without myelin and impulse ‘jumps’ from one node to next