Neoplasia I Flashcards

1
Q

neoplasia

A

process of uncontrolled growth

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2
Q

neoplasm/tumor

A

abnormal mass of tissue

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3
Q

can neoplasms be physiological?

A

no

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4
Q

what is central to development of neoplasm

A

DNA damage

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5
Q

benign tumor

A

grows without invading

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6
Q

maligant tumor

A

invades

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7
Q

intermediate tumor

A

locally invasive
not benign
no tendency for metastasis

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8
Q

carcinoma in situ

A

pre-invasive cell proliferation

cytological features of maligancy

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9
Q

parenchya tumor

A

comprised of clonal neoplastic cells

soft

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10
Q

stroma tumor

A

comprised of CT, blood vessels, macrophages, lymphocytes

hard

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11
Q

two components of tumor

A

stroma

parenchyma

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12
Q

benign suffix

A

oma

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13
Q

malignant suffix

A

sarcoma

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14
Q

cystademona

A

adenomas with cavities or cysts

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15
Q

polyp

A

club shaped growth

benign epithelial tumor or hyperplasa

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16
Q

where are polyps located

A

projects from mucosal surface into lumen of hollow viscus

17
Q

papilloma

A

benign

produces finger-like/warty projections

18
Q

maligant tumors with oma

A
melanoma
lyphoma
seminoma
hepatoma
astrocytoma
19
Q

choristoma

A

normal tissue that is located in the wrong place

20
Q

hamartoma

A

right tissue at the right place but it’s disorganized

21
Q

general features of carcomas

A

no capsule
rapid growth
invasion
atypical mitosis

22
Q

general features of benign tumors

A

capsule
slow growth
no invasion
no atypical mitosis

23
Q

sarcoma

A

mesenchymal orgiin

24
Q

carcinoma

A

epithelial cell origin

25
Q

what has a better prognosis sarcoma or carcinoma

A

carcinoma

26
Q

transitional cell carcinoma

A

origin is transitional epithelium in urinary system

27
Q

lymphoma is derived from what

A

lymphoid tissue

28
Q

what is the most common extranodal site for primary maligant lymphoma

A

stomach

29
Q

leukemia is derived from what

A

bone marrow stem cells

30
Q

what is most common adult leukemia and overal leukima

A

CLL

31
Q

what is most common childhood leukoma

A

ALL

32
Q

teratoma

A

tumor composed for more than one parenchymal cell type

derived form more than 1 germ layer

33
Q

benign teratoma is also called

A

mature

34
Q

maligant teratoma is also called

A

immature

teratocarcinoma

35
Q

peutz-jeghers syndrome

A

automsomal dominante

benign polyps in GI tract and hyperpigmented macules

36
Q

monoconality

A

origin of tumors from precursor cell

37
Q

what are monoclonal

A

neoplasms

38
Q

what are polyclonal

A

non-neoplastic proliferations

39
Q

4 criteria to tell if it’s malignat

A

rate of growth
differentiaion and anaplasia
local invasion
metassis