Neoplasia I Flashcards

1
Q

neoplasia

A

process of uncontrolled growth

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2
Q

neoplasm/tumor

A

abnormal mass of tissue

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3
Q

can neoplasms be physiological?

A

no

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4
Q

what is central to development of neoplasm

A

DNA damage

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5
Q

benign tumor

A

grows without invading

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6
Q

maligant tumor

A

invades

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7
Q

intermediate tumor

A

locally invasive
not benign
no tendency for metastasis

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8
Q

carcinoma in situ

A

pre-invasive cell proliferation

cytological features of maligancy

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9
Q

parenchya tumor

A

comprised of clonal neoplastic cells

soft

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10
Q

stroma tumor

A

comprised of CT, blood vessels, macrophages, lymphocytes

hard

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11
Q

two components of tumor

A

stroma

parenchyma

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12
Q

benign suffix

A

oma

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13
Q

malignant suffix

A

sarcoma

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14
Q

cystademona

A

adenomas with cavities or cysts

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15
Q

polyp

A

club shaped growth

benign epithelial tumor or hyperplasa

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16
Q

where are polyps located

A

projects from mucosal surface into lumen of hollow viscus

17
Q

papilloma

A

benign

produces finger-like/warty projections

18
Q

maligant tumors with oma

A
melanoma
lyphoma
seminoma
hepatoma
astrocytoma
19
Q

choristoma

A

normal tissue that is located in the wrong place

20
Q

hamartoma

A

right tissue at the right place but it’s disorganized

21
Q

general features of carcomas

A

no capsule
rapid growth
invasion
atypical mitosis

22
Q

general features of benign tumors

A

capsule
slow growth
no invasion
no atypical mitosis

23
Q

sarcoma

A

mesenchymal orgiin

24
Q

carcinoma

A

epithelial cell origin

25
what has a better prognosis sarcoma or carcinoma
carcinoma
26
transitional cell carcinoma
origin is transitional epithelium in urinary system
27
lymphoma is derived from what
lymphoid tissue
28
what is the most common extranodal site for primary maligant lymphoma
stomach
29
leukemia is derived from what
bone marrow stem cells
30
what is most common adult leukemia and overal leukima
CLL
31
what is most common childhood leukoma
ALL
32
teratoma
tumor composed for more than one parenchymal cell type | derived form more than 1 germ layer
33
benign teratoma is also called
mature
34
maligant teratoma is also called
immature | teratocarcinoma
35
peutz-jeghers syndrome
automsomal dominante | benign polyps in GI tract and hyperpigmented macules
36
monoconality
origin of tumors from precursor cell
37
what are monoclonal
neoplasms
38
what are polyclonal
non-neoplastic proliferations
39
4 criteria to tell if it's malignat
rate of growth differentiaion and anaplasia local invasion metassis