Hemodynamic Disorders V Flashcards
infarction
death of tissue due to interruption in blood supply
time until cellular death due to hypoxia of neuron
3-4 minutes
time until cellular death of due to hypoxia of myocardium
20-30 minutes
time until cellular death of fibroblast due to hypoxia
hours
what is the typical shape of infartion
wedge-shaped
When do you get a red (hemorrhagic) infart
venous occlusion
loose tissues
tissues w/dual circulation
tissues previously congested due to sluggish flow
re-established blood flow to a site of previous arterial occlusion and necrosis
white (anemic) infart
typically of arterial occlusion in solid organs with limitation of blood flow into areas of ischemic necrosis
what is the dominant histologic characteristic of infarction
ischemic coagulative necrosis
how can you tell that an MI is several days old based on histology
dense polymorphonuclear leukocytic inflammatory infilitrate
when do you get a septic infarct
when the origin of an embolus is infected tissue
what is the major source of septic emboli
vegetations formed by bacteria growing on heart valves in bacterial endocarditis
shock
inadequate blood flow secondary to decreased CO or maldistributed output that results in irreversible tissue damage
sequela of shock
hypotension
impaired tissue perfusion
cellular hypoxia
examples of things that can cause cardiogenic shock
infarction
arrythmia
tamponade
pulmonary embolism
examples of things that can cause hypvolemic sshock
hemorrhage
fluid loss
burns
trauma