Neoplasia 3: Chemical Initiatiors of Chemical Carcinogenesis Flashcards
1
Q
Direct
A
Cyclophosphamide, chlorambucil, busulfin, melphalan
2
Q
Indirect: Polyacylic Aromatic Hydrocarbons
A
From: Cigs, smoked meat and fish
Effect: lung, bladder, and pancreatic cancers, small cell and squamous cell carcinoma (smoking)
3
Q
Indirect: Aromatic Amines and Azo Dyes
A
Acetyl-aminoflorene and azy dyes –> hepatocellular carcinomas
4
Q
Indirect: Beta-naphthylamine
A
Bladder cancer form aniline dye and rubber industry exposure