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M3 Path B1 > Neoplasia 2: Growth Factor Receptors (Oncogenic Activation) > Flashcards

Neoplasia 2: Growth Factor Receptors (Oncogenic Activation) Flashcards

1
Q

EGF Receptor Family - ERBb1 (EGFR)

A

Mutation

Adenocarcinoma of lung

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2
Q

EGF-Receptor Family - ERBb2 (HER)

A

Amplification

Breast carcinoma

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3
Q

RET (receptor for neurotrophic factors)

A

Point Mutation

Multiple Endocrine Neoplasia (MEN) 2A and 2B
Familial medullary thyroid carcinomas

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4
Q

KIT (receptor for KIT ligand)

A

Point Mutation

GI stromal tumors
Seminomas (are malignant)
Leukemias

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M3 Path B1 (29 decks)

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