NCMB312 FINALS

Question 1

discovered of Vibrio cholera.

Answer 1

Filippo Pacini

Question 2

Russian-Jewish bacteriologist - developed the first cholera vaccine in July 1892.

Answer 2

Waldemar Haffkine

Question 3

• is regarded as one of the founding fathers of modern epidemiology and
  discovered how cholera was spread in London.

Answer 3

Dr. John Snow

Question 4

• has been nicknamed the “blue
  death” because a person dying
  of this may lose so many body fluids that their skin turns bluish-gray.

Answer 4

Cholera

Question 5

Causative Agent of cholera

Answer 5

Vibrio coma or vibrio cholera

Question 6

Incubation Period
From a few hours to 5 days
(average of 3 days)

Answer 6

cholera

Question 7

Period of Communicability
As long as microorganisms are
present in the bowel excreta

Answer 7

cholera

Question 8

Mild-diarrhea that becomes voluminous
Rice-watery stool (pathognomonic
sign)
Washer woman’s hands

Answer 8

cholera

Question 9

Effortless vomiting
Cramping of the extremities
(hypokalemia)
Signs of severe dehydration

Answer 9

cholera

Question 10

Severe dehydration and ECF
volume deficit
Hypokalemia
Metabolic acidosis

Answer 10

cholera

Question 11

Stool or vomitus culture
Serum electrolytes
Dark field or Phase
Microscopy

Answer 11

cholera

Question 12

Antibiotics for cholera

Answer 12

Tetracycline
(drug of choice)

Question 13

Rice watery stool
Signs of severe
dehydration:
sunken eyeball,
Washer- woman’s
hand, metabolic
acidosis, shock

Answer 13

Violent Dysentery Cholera, Vibrio cholera

Question 14

Tx: Tetracycline

Answer 14

Violent Dysentery Cholera, Vibrio cholera

Question 15

+/- fever
+/- vomiting
Abdominal pain
(colicky or
cramping)
Diarrhea with
tenesmus
Mucus and Blood
streaked stool

Answer 15

Bacillary Dysentery
Shigelosis
Shigella dysenteriae

Question 16

Tx: Cotrimoxazole

Answer 16

Bacillary Dysentery
Shigelosis
Shigella dysenteriae

Question 17

+/- fever
+/- vomiting
Abdominal pain
Diarrhea with
tenesmus
Muco-purulent
blood streaked
stool
Tx: Metronidazole

Answer 17

Amoebic Dysentery
Amoebiasis
Entamoeba
histolitica

Question 18

Tx: Metronidazole

Answer 18

Amoebic Dysentery
Amoebiasis
Entamoeba
histolitica

Question 19

The first effective vaccine for typhoid was developed by - and was introduced for military
use in 1896.

Answer 19

Almroth Edward Wright

Question 20

• was a pathologist that confirmed the bacillus Eberthella typhi, which is known today as Salmonella enterica.

Answer 20

Georg Gaffky

Question 21

Causative Agent Salmonella Typhi

Answer 21

TYPHOID FEVER

Question 22

Incubation Period
Variable
Usually 1 – 3 weeks, average: 2weeks

Answer 22

TYPHOID FEVER

Question 23

Mode of Transmission
Fecal – oral route
Ingestion of contaminated food and
water 5 F’s – fingers, feces, flies, food,
fomites

Answer 23

TYPHOID FEVER

Question 24

Clinical Manifestations
Gradual onset
A-norexia and abdominal pain
B-radycardia
C-onstipation

Answer 24

TYPHOID FEVER

Question 25

D-iarrhea, D-evelop skin eruptions
on the abdomen, back and chest
(ROSE SPOTS)
E-nlarged spleen
F-ever and chills
G-eneralized body weakness
H-eadache

Answer 25

TYPHOID FEVER

Question 26

Diagnostic Exams
CBC
Widal test
Typhidot exam
Blood culture
Urine and stool culture

Answer 26

TYPHOID FEVER