Naloxone

Question 1

Presentation

Answer 1

0.4mg in 1ml

Question 2

Indications

Answer 2

1. Altered conscious state with respiratory depression secondary to administration of opioids

Question 3

Contraindications

Answer 3

1. Nil significance

Question 4

Precautions

Answer 4

1. If Pt is known to me physically dependent on opioids be prepared for combativeness
2. Neonates

Question 5

Side effects

Answer 5

1. Sweating, goose flash, tremor
2. Nausea and vomiting
3. Agitation
4. Dilated pupils
5. Convulsions

Question 6

Pharmacology

Answer 6

Naloxone is a competitive opioid antagonist which competes with opioids at receptors sites to reverse effects of opioids

Question 7

IV effects

Answer 7

Onset - 1-3mins
Peak - n/a
Duration - 30-40mins

Question 8

IM effects

Answer 8

Onset - 1-3 mins
Peak - n/a
Duration - 30-45mins