Aspirin Flashcards
1
Q
Presentation
A
300mg tablet
2
Q
Indications
A
ACS
3
Q
Contraindications
A
- Actively bleeding peptic ulcer
- suspected dissection AAA
- Bleeding disorders
- Hypersensitivity
- Chest pain associated with Psycho stimulant OD with SBP >160
4
Q
Precautions
A
- Peptic ulcers
- Asthma
- Pts on anticoagulants
5
Q
Side effects
A
- Longer bleeding times
- Heartburn, GI bleeding, nausea
- Hypersensitivity reactions
6
Q
Pharmacology
A
Aspirin is an analgesic, antipyretic, anti inflammatory and anti-platelet aggregation agent. Aspirin minimises platelet aggregation and thrombus formation in order to retard the progression of coronary artery thrombosis in ACS. Aspirin also inhibits synthesis of prostaglandins.
7
Q
Metabolism
A
Aspirin is converted to salicylate in the gut mucosa and liver
8
Q
Excretion
A
Excreted by the kidneys
9
Q
Oral effects
A
Onset - N/A
Peak - N/A
Duration - 8-10hrs