Morphine

Question 1

Presentation

Answer 1

10mg in 1ml

Question 2

Indications

Answer 2

1. Analgesia
2. Sedation for intubation
3. Sedation to maintain intubation

Question 3

Contraindications

Answer 3

1. Hypersensitivity
2. Late 2nd stage labour
3. Renal failure

Question 4

Precautions

Answer 4

1. Elderly/frail
2. Current asthma
3. Acute Alcoholism
4. Respiratory tract burns
5. Respiratory depression
6. Known addict
7. Pts on MOI
8. Hypotension

Question 5

Side effects

Answer 5

1. Drowsiness
2. Respiratory depression
3. Addiction
4. Pin point pupils
5. Nausea
6. Euphoria
7. Hypotension
8. Bradycardia

Question 6

Pharmacology

Answer 6

Morphine is an opioid analgesic which works on opioid receptors kappa, delta, mu, and sigma. Activation of the above receptors results in depression, respiratory depression, stimulation and dependence. Other results include vasodilation and decreased conduction through the AV node.

Question 7

IV effects

Answer 7

Onset - 2-5mins
Peak - 10mins
Duration - 1-2hrs

Question 8

IM effects

Answer 8

Onset - 10-30mins
Peak - 30-60mins
Duration - 1-2hrs