Myocarditis path Flashcards

1
Q

noninfectious myocarditis

A
  • hypersensitivity, immune related (RF, RA, SLE, scleroderma, drug rxn)
  • radiation
  • epicardial surface smooth, glistening, scattered small yellow microabscesses
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2
Q

types of infectious myocarditis

A
viral
bacterial
aids
fungal
chagas disease/parasitic
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3
Q

viral myocarditis

A
  • Coxsackie A/B, influenza, CMV, HIV, rubellla
  • T cells
  • macrophages
  • giant cells
  • focal necrosis
  • after Hx of URI
  • severe in children/pregnancy
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4
Q

bacterial myocarditis

A
  • staph, strep, meningococcal, Lyme

- bacterial colonies + PMNs

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5
Q

AIDS myocarditis

A

-opportunistic infection
-T cells, macrophages, giant cells, AND PLASMA CELLS
-

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6
Q

fungal myocarditis

A
  • toxoplasmosis, aspergillosis, candida
  • acute inflammatory cells, GMS stain
  • MIX OF ACUTE/CHRONIC cells
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7
Q

chagas disease

A
  • parasitic myocarditis
  • acute: pseudocyst, inflammation, necrosis
  • chronic: interstitial fibrosis, hypertrophy, mural thrombi formation
  • chagoma
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8
Q

giant cell myocarditis

A
  • idiopathic
  • associated with SLE, hyperthyroidism, thymoma
  • flabby/dilated
  • necrosis
  • granulomatous inflammation (not circumscribed)
  • giant cells
  • CHF
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