Myocarditis path Flashcards
1
Q
noninfectious myocarditis
A
- hypersensitivity, immune related (RF, RA, SLE, scleroderma, drug rxn)
- radiation
- epicardial surface smooth, glistening, scattered small yellow microabscesses
2
Q
types of infectious myocarditis
A
viral bacterial aids fungal chagas disease/parasitic
3
Q
viral myocarditis
A
- Coxsackie A/B, influenza, CMV, HIV, rubellla
- T cells
- macrophages
- giant cells
- focal necrosis
- after Hx of URI
- severe in children/pregnancy
4
Q
bacterial myocarditis
A
- staph, strep, meningococcal, Lyme
- bacterial colonies + PMNs
5
Q
AIDS myocarditis
A
-opportunistic infection
-T cells, macrophages, giant cells, AND PLASMA CELLS
-
6
Q
fungal myocarditis
A
- toxoplasmosis, aspergillosis, candida
- acute inflammatory cells, GMS stain
- MIX OF ACUTE/CHRONIC cells
7
Q
chagas disease
A
- parasitic myocarditis
- acute: pseudocyst, inflammation, necrosis
- chronic: interstitial fibrosis, hypertrophy, mural thrombi formation
- chagoma
8
Q
giant cell myocarditis
A
- idiopathic
- associated with SLE, hyperthyroidism, thymoma
- flabby/dilated
- necrosis
- granulomatous inflammation (not circumscribed)
- giant cells
- CHF