Myeloproliferative neoplasms Flashcards
1
Q
myeloproliferative neoplasm defintion
A
clonal haemopoietic stem cell disorders with an increased production of one or more types of haemopoietic cells
2
Q
contrast between acute leukaemia and myeloproliferative
A
maturation is relatively preserved in myeloproliferative
3
Q
BCR ABL1 negative
A
polycythaemia vera
essential thrombocytopenia
primary myelofibrosis
4
Q
BCR ABL 1 positive
A
chronc myeloid leukaemia
5
Q
features common to MPN
A
asymptomatic
increased cellular turnover- gout, fatigue, weight loss, swets
symptoms signs due to splenomegaly
marrow failure
thrombosis
6
Q
A
