Mutations and Genes

Question 1

The Locations of Mutations in Genes

Answer 1

Mutations happen anywhere in DNA

Question 2

What happens when a codon is changed to a codon for a different amino acid in a protein-coding region?

Answer 2

A missense mutation

Question 3

What happens when there is a deletion of 3 bp in a protein-coding region?

Answer 3

A loss of amino acid

Question 4

What happens when there are mutations in the promoter?

Answer 4

No mRNAs

Question 5

What happens when there are mutations in regulatory regions?

Answer 5

Too few or too many mRNAs

Question 6

What happens when there are mutations at splice sites?

Answer 6

Intron left in (or removed wrong) which leads to defective mRNAs

Question 7

Sickle Cell Disease Mutation

Answer 7

DNA: AT to TA bp substitution
RNA: GAA TO GUA at codon 6

Question 8

EMS makes GC to AT bp substitutions. What would happen if EMS mutated a 5’-CTT-3’ codon?

Answer 8

Leu to Phe

Question 9

Parsimony

Answer 9

The simplest explanation is the correct one

Question 10

Forward Mutations

Answer 10

Wild type allele to mutant allele

Question 11

Reverse Mutations

Answer 11

Mutant allele to wild type allele