Chromosome Rearrangements

Question 1

What are the 4 major types of rearrangements?

Answer 1

Deletion
Duplication
Inversion
Translocation

Question 2

What are the subtypes of deletion rearrangements?

Answer 2

Terminal deletion

Interstitial deletion

Question 3

What are the subtypes of duplication rearrangements?

Answer 3

Tandem duplication

Insertional duplication

Question 4

What are the subtypes of inversion rearrangements?

Answer 4

Pericentric inversion

Paracentric inversion

Question 5

What are the subtypes of translocation rearrangements?

Answer 5

Reciprocal translocation

Robertsonian translocation

Question 6

What are nonallelic homologous recombinations?

Answer 6

CO at the wrong location so there is a chromosome rearrangement

Question 7

What are unbalanced rearrangements?

Answer 7

Deletions are an unbalanced rearrangements

Question 8

Can a person be homozygous for a deletion?

Answer 8

No

Question 9

Can a person be heterozygous for a large deletion?

Answer 9

No

Question 10

What are balanced rearrangements?

Answer 10

Inversion and translocations change the location but not the number of genes