Muscle Tissue Flashcards
Properties of muscle tissue
- Excitability
– Receive and respond to stimuli - Conductivity
– Conduct electricity along membrane - Contractility
– Shorten forcibly when stimulated - Extensibility
– Ability to be stretched - Elasticity
– Ability to recoil to resting length
Functions of muscle tissue
- Body movement
- Maintain posture & stabilize joints
- Protect & support
- Open & close body passageways
- Generate heat
When a group of muscle fibers is “bundled” as a unit within the whole muscle it is called a
fascicle
1) Muscle
2) Fascicle
3) Muscle cell/muscle fiber
4) Myofibril
5) Sarcomere
6) Filaments- actin and myosin
1) Multiple bundles housing many muscle fibers
2) A bundle of muscle fibers
3) Elongated, multinucleated, cylindrical cell
4) Long, cylindrical contractile element within muscle cell
5) A sarcomere is the basic contractile unit of muscle fiber
6) Short contractile proteins of two types: thick and thin
Endomysium
Perimysium
Epimysium
Fascia
Endomysium, perimysium, and
epimysium merge to form a tendon
Endomysium
– Areolar connective
– Around each muscle fiber
- Perimysium
– Sheath around fascicle - Fascicle = bundle of muscle fibers
Epimysium
– Sheath around group of fascicles
- Fascia
– Covering outside epimysium
– Hypodermis - Endomysium, perimysium, and
epimysium merge to form a tendon
Skeletal Muscle: Attachments
Direct—epimysium fused to:
* Periosteum of bone
* Perichondrium of cartilage
– Indirect—connective tissue wrappings extend beyond muscle
* Rope-like tendon
* Sheet-like aponeurosis
Origin vs insertion
- Insertion – movable bone
- Origin – immovable (less movable) bone
Axial vs Appendicular
Attach in at least two places
– Axial
* Superior attachment
* Inferior attachment
– Appendicular
* Proximal attachment
* Distal attachment
Microscopic Anatomy of a Skeletal Muscle Fiber
- Long, cylindrical cell (up to 20 cm)
- Multiple peripheral nuclei from fusion of myoblasts during development
- Satellite cells (stem cells) can form myoblasts after damage
Sarcolemma = plasma membrane
- Sarcoplasm = cytoplasm
Myofibrils= Densely packed, rodlike elements. About 80% of cell volume.
Contain sarcomeres - contractile units. Region between two successive Z discs. M line runs down the middle. A band (Dark) – where there is myosin. I band (White)– the area around the Z disc where there is no myosin. H zone – the area around the M line where there is no actin.
Sarcomeres contain myofilaments. -
-Actin myofilaments = thin filaments, anchored to Z discs. Myosin myofilaments = thick filaments. Connected at M line.
Neuromuscular junction
– Neuron–muscle connection
– Synaptic knob (axon terminal) of
neuron contacts sarcolemma of
muscle cell
– Also called a motor end plate
Muscle contraction
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Muscle structure
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Physiology of muscle contraction
Action potential arrives at axon terminal at neuromuscular junction
Action potential in sarcolemma
Neurotransmitter (Ach) is released
Local depolarization
Ion channels on sarcolemma open
AP travels across the entire sarcolemma
AP travels down T tubules
SR releases Ca2+;
Myosin heads bind to actin
Contraction begins
A motor unit consists of
1 neuron + all of the muscle fibers it contacts
1) Isometric contractions
2) Isotonic contractions
1) Load greater than tension
muscle can develop. Tension increases to muscle’s capacity, but
muscle neither shortens nor
lengthens. Cross bridges generate force but do not move actin
filaments.
2) Muscle changes in
length and moves load– Thin filaments slide.
A) Concentric contractions – muscle shortens and does work
B) Eccentric contractions – muscle generates force as it lengthens