Muscle Systems Flashcards
how do muscles contract
Skeletal, Cardiac, Smooth muscles all use sliding filament contractile mechanism
muscle fibers
are large and multinucleated; formed from the fusion of embryonic
myoblasts. Each muscle consists of many muscle fibers bundled together by connective
tissue.
muscles
attached to the skeleton via connective tissue called tendons
two types of skeletal muscle
slow twitch and fast twitch
sarcomeres
units of contraction
skeletal muscle
made up of bundles of muscle fibers
myofibrils
highly ordered assemblages of thick myosin and thin actin filaments
steps of muscle contraction
Motor nerve action potential arrives at the motor end plate
- Acetylcholine released, sarcolemma and membranes depoloarized
- Action potential transmitted via T-tubules to sarcoplasmic reticulum
- Ca2+ release from SR terminal cisternae into sarcoplasm
- Ca2+ bound by troponin
- Tropomyosin shift from actin binding site and actin-myosin cross bridge formation
- Myosin ATPase activated and ATP hydrolyzed
for contraction, muscle requires
energy
Muscles have three systems for supplying ATP for contractions
immediate system: uses preformed ATP and creatine phosphate
glycolytic system: metabolizes carbohydrates to lactic acid and pyruvate
oxidative systm: metabolizes carbohydrates or fats to H2O and Co2
creatine
a supplement that helps espcially sprnters
glycolytic system
glycolysis: faster process that supplies ATP
oxidative system
ETC + Krebs/oxidative phosphorylatoion
slower process that supplies ATP