Development Flashcards
Development
The process in which a multicellular
organism undergoes a series of progressive changes that
characterizes its life cycle
embryo
a plant or animal in its earliest stages
can be protected in a seed, an egg shell, or a
uterus.
Four processes of development
Determination
differentiation
morphogenesis
growth
Determination
sets the fate of the cell
differentiation
process by which different types
of cells arise
morphogenesis
organization and spatial
distribution of differentiated cells to create shapes
involves differential gene expression and can occur
in several ways:
occurs in several ways Cell division • Cell expansion (in plant development) • Cell movements are important in animal • Apoptosis (programmed cell death) is essential in organ development
growth
increase in body size by cell division and
cell expansion
occurs by increasing the number of cells or enlargement of
existing cells.
As development proceeds, the potential of cells becomes
more restricted
cell fate is influenced by
the extracellular environment, as well as
changes in gene expression.
Determination and differentiation occur because of
differential
gene expression.
transcriptional controls
Major controls of gene expression in differentiation
embryonic stem cells
Early animal embryonic cells have totipotency.
Each cell can develop into a complete embryo.
pluripotent
Cells of the blastula or blastocyst are more
“determined” and cannot form a complete
embryo
induced pluripotent stem cells
from adult
tissue is now the way stem-cell research is
heading.
Fertilization does several things
Blocks entry of additional sperm
•Stimulates ion flux across membrane
•Changes pH of the egg
•Increases egg metabolism and protein synthesis
•Initiates cell division
•Sperm contributes haploid DNA
•Sperm contributes a centriole (not in all species)
in mammals cleavage is
rotational
First cell division is parallel to the animal–vegetal axis—yields two blastomeres.
In second division two blastomeres divide at right angles to each other— one is parallel to the axis and the other is perpendicular to it.
mammalian cleavage is
slow and asynchronous.
When the zygote reaches eight cells, the blastomeres change shape to
maximize contact with one another
When a blastula reaches 16 to 32 cells, it divides into two groups:
• Inner cell mass—becomes the embryo
• Trophoblast—a sac that forms from the outer cells. Its cells secrete fluid and
create the blastocoel, with the inner cell mass at one end
Embryo is now called a blastocyst.
implantation
occurs when
the trophoblast adheres
to the endometrium, or
uterine lining.
ectopic or tubal pregnancy
Early implantation that
occurs in the oviduct
specific blastomere cells
*cells that are part of the blastula
undergo development into
the specific tissues and
organs.
fate maps
identify which cells
in the blastula will become
the particular tissues and
organs
ectoderm
outer germ layer
forms epidermal layer of the skin
becomes the nervous system,
the eyes and ears, and the skin
neural ectoderm
midline
will form the nervous system