Ch 3: Proteins, Carbohydrates, and Lipids Flashcards
macromolecules
proteins, lipids, carbohydrates, and nucleic acids
proteins
made up of amino acids
aka protein, peptide, polypeptide
has many functions
amino acids
make up proteins
20 different types
polypeptide chain
single, unbranched, chain of amino acids
peptide bond
amino acids bond together covalently in a condensation reaction
condensation reaction
loss of H2O molecule
hydrophobic amino acids
hydrophobic if R groups don’t contain O or N
glycine (G): smallest amino acid
alanine(A): simplest with aliphatic R-group
Phenylalanine (F): simplest with aromatic R group
Hydrophilic amino acids
R group contains O or N
Lysine (K): pos charged
aspartate (D): neg charged
serine (S): -OH, hydroxyl group
exceptions to the rule
tyrosine and tryptophan
amino acids are often modified after translation
most common modification is phosphorylation,
occurs on the -OH group of serine, threonine, and tyrosine
isomers
molecules with the same chemical formula, but atoms are arranged differently
structural isomers
differ in how their atoms are joined together
primary structure
1˚
amino acid sequence
secondary structure
2˚
wavy structure
shape adopted by the amino acid backbone
alpha helix or B pleated sheet
tertiary structure
3˚
folded 3-D structure