Muscle Physiology ML 5

Question 1

What is the structure of smooth muscle

Answer 1

arranged diagonally and thing filaments are anchored to plasma membrane or dense bodies

Question 2

5 ways to excite oor activate cells

Answer 2

NT
Hormones
Local factors
Strecth
Spontaenous Electrical Actvity

Question 3

Pacemaker potential

Answer 3

slowly depolarizes membrane to threshold and AP occurs
-always leads to contraction

Question 4

Slow wave oattern

Answer 4

stimulus applied and it depolarizes and AP occurs at peak which leads to contraction

Question 5

What is tone

Answer 5

continuous and partial contraction

Question 6

Why does tone occur

Answer 6

the continous presence of intraceullar calcium which allows XBs to happen

Question 7

What are the two sources of cytosolic calcium

Answer 7

extraceullar and intracellular

Question 8

extracellular calcium

Answer 8

enter the cell thrugh calcium channels
-doesnt always lead to an AP

Question 9

Intraceullar calcium

Answer 9

release from SR
-metabolic receptors are couple to G proteins
-acivtion leads to release of Ip3
-IP3 can bind to receptord on the SAR and release calcium
-contraction occur but no AP needeed