Muscle Physiology ML 2 Flashcards
Skeletal muscle is a ___ tissue that propagates APs along its _____
excitable tissue; membrane
What part of the PNS coordinates with skeletal muscle
somatic motor division
What is the motor plate of the NMJ
highly folded region of the sarcolemma that lives directly beeneth the alpha motor neuron terminals
What does the motor plate have
high concentrations of nACh receptors which are ligand gates ionotropic receptors
Botox
breaks down snare protreins and affects ACh release which reduces activity of muscles
Pesticides and Nerve Gas
inhibit activity of enzyme so Ach stays bound to receptor (paralysis and no repol)
Plant Toxin
antagonist: binds to receptor and blacks Ach
-inhibits process and causes paralysis
Syntheitc
Agonist: bind to receptor and causes paralysis