Endocrine Physiology ML:2 Flashcards
What do hormone receptors determine?
Which tissues respond to an endocrine “broadcast”
High sensitivity:
receptors respond to low concentrations of circulating hormones
What do huge signal amplications allow?
allows hormones to act quickly due to their signal transduction mechanisms
High concentrations of hormone=
low receptor number
Low concentrations of hormone =
up regulation so high receptor number
What does having a permissive effect mean?
with a thyroid hormone around we get more epinephrine receptors
Inputs that control hormone secretion?
ions or nutrients
neurotransmitters
hormones
Tropic Hormone
a hormone that affects the secretion of another hormone
Trophic hormone
a hormone that promotes growth/health of a stimulated gland
Hypersecretion:
mainly caused by tumors that ignore negative feedback or abnormally increased amount of tropic hormones
Hyposecttrion
gland destruction or loss of tropic hormones
Hyperresponsiveness
receptor upregulation or second messenger pathway over activation
Hyporesponsiveness
receptor downregulation or second messenger pathway under activation