Muscle Models Flashcards

1
Q

aponeurosis

A

like a tendon, connective tissue layer forms a thin, flattened sheet of dense irregular tissue

connect muscle to bone

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2
Q

deep fascia

A

additional expansive sheet of dense irregular connective tissue external to epimysium

separates individual muscles, binds muscles with similar functions, contains nerve, blood, lymph vessels, fill space between muscles

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3
Q

endomysium

A

between fascicles

innermost layer, delicate areolar connective tissue layer surrounds and electrically insulates each muscle fiber

reticular protein fibers help bind neighboring muscle fibers and support capillaries

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4
Q

epimysium

A

wraps muscle

layer of dense irregular connective tissue surrounding whole skeletal muscle

protection

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5
Q

fascicles

A

bundles of many organized muscle fibers (myofibers)

keep together

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6
Q

gap junctions

A

protein pores between sarcolemma of adjacent cardiac muscle cells; provide low-resistance pathway for ion flow allowing action potential to move continuously resulting in synchronous contraction

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7
Q

muscle fibers (cells)

A

in fascicles

skeletal muscle cells, extraordinarily long, mulinucleated because of fused myoblasts

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8
Q

myofibrils

A

long, cylindrical structures composing 80% of volume of a muscle fiber; contain myofilaments

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9
Q

perimysium

A

around fascicles

surrounds fascicles, dense irregular connective tissue sheath contains extensive blood vessels and nerves that branch to supply muscle fibers within each fascicle

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10
Q

tendons

A

thick, cord like structure, dense regular connective tissue, 3 layers as they merge and extend past muscle fibers

attach muscle to bone, skin, or another muscle

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11
Q

A bands

A

central region of sarcomere containing entire thick filament; thin filaments partially overlap on ends

never changes length

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12
Q

Actin

A

protein of thin filaments

contains myosin binding site

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13
Q

H zone

A

no actin, most central portion of A band in a resting sarcomere, no thin filament overlap- only thick

disappears when thin is pulled past thick during maximum muscle contraction

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14
Q

I bands

A

extend from both ends of and are bisected by the Z disc, contain only thin filaments (light)

disappears during contraction as thin filaments are pulled past thick filaments

changes length during contraction

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15
Q

M line

A

thin transverse protein meshwork structure in center of H zone serving as attachment site for thick filaments and keeps thick filaments aligned during contraction/relaxation events

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16
Q

motor end plate

A

specialized region of sarcolemma with numerous folds to increase surface area covered by synaptic knob, vast acetylcholine receptors

17
Q

motor neuron

A

nerve cells that transmit nerve signals from brain or spinal cord, axon branches to innervate numerous skeletal muscle fibers

18
Q

motor unit

A

single motor neuron and the muscles it controls

size determines the degree of control

19
Q

myofilaments

A

bundles of muscle protein fiber

20
Q

myosin

A

protein makes up thick filaments; 2 strands with globular head and elongated tail

site for ATP to break into ADP and Pi

21
Q

sarcolemma

A

plasma membrane of a skeletal muscle fiber

22
Q

sarcomere

A

composed of overlapping thick and thin filaments, repeating microscopic cylindrical units

23
Q

sarcoplasmic reticulum

A

internal membrane complex similar to smooth endoplasmic reticulum, surround bundles of myofibrils

24
Q

synaptic cleft

A

extremely narrow fluid-filled spec separating synaptic knob and motor end plate

residing place of acetylcholinesterase (AChE)

25
Q

T tubules

A

transverse tubules

deep invaginations of sarcolemma extending into muscle fibers as a network of narrow membranous tubules

contain NA/K pumps and channels used for muscle contraction

26
Q

terminal cisterns

A

blind sacs at ends of individual sections of sarcoplasmic reticulum surrounding t- tubule

serve as reservoirs for Calcium cation

27
Q

thick filaments

A

about 11 nanometer diameter made of 200-500 myosin protein molecules

28
Q

thin filaments

A

about 5-6 nanometer diameter made of 2 strands of twisted/helical actin protein

29
Q

tropomyosin

A

short, thin, twisted filament, “string like” protein

cover actin strands and myosin binding sites

30
Q

troponin

A

globular/ ball-like protein attached to tropomyosin

binding site for calcium cation

31
Q

Z disc

A

composed of specialized proteins positions perpendicular to myofilaments and serve as anchors for thin filaments

delineate ends of the sarcomere

32
Q

Order of skeletal muscle

A
thick- myosin and thin- actin
myofilaments
myofibrils
muscle fiber (wrapped in endomysium)
fascicle (wrapped in perimysium)
skeletal muscle (wrapped in epimysium)