MSK Microbiology Flashcards
1
Q
Acute BJI organisms and management
A
- Staph aureus, Strep
- Empirical Abx: flucloxacillin
2
Q
Chronic BJI management
A
- Take samples and only start empirical if SIRS
- Coagulase negative strep
3
Q
PJI
A
- Min of 3 bones/tissue/pus samples for culture
- Min 6 weeks Abx before cleaning
4
Q
Abx in PJI
A
- Flucloxacillin for gram positive strep
- Vancomycin if allergic
- Co-trimoxazole and Amoxicillin for gram negative strep
5
Q
PJI: Retention of prothesis (DAIR) antibiotic regime
A
4 weeks IV + 8 weeks oral
6
Q
PJI: 1 stage antibiotic regime
A
4 weeks IV + 8 weeks oral
7
Q
PJI: 2 stageantibiotic regime
A
6 weeks IV + 6 weeks oral
8
Q
PJI: hip and knee antibiotic regime
A
- Hip 3 months
- Knee 6 months
9
Q
Early post op (0-3months)
- Route of infection
- Cause
A
- Perioperative with fever, effusion, warmth and drainage
- Staph aureus, Strep, Enterococci
10
Q
Delayed post op (3-24months)
- Route of infection
- Cause
A
- Perioperative with persistent pain, device loosening, fistula
- Coagulase negative staph, p.acnes
11
Q
Late infection (>24mnths)
- Route of infection
- Cause
A
- Haematogenous with acute or subacute signs
- Staph aureus or ecoli
12
Q
Risk factors for PJI
A
RA, diabetes, obesity, malnutrition
13
Q
Septic Arthritis
- Route
- Organisms
- Treatment
A
- Haematogenous or trauma
- MSSA, Strep
- Flucloxacillin for Staph Aureus
- Ceftrixone
14
Q
Osteomyelitis
- Cause
- Spread
A
- Inflammation of bone and medullary cavity
- Acute or chronic
- Haematogenous, Continguous, Prosthesis and Peripheral vascular associated
15
Q
Acute Osteomyelitis
-time frame
A
Few days-2weeks
