MSK differential Dx Flashcards
(Males or Females) Who commonly experiences OA more often before 50 y/o?
Men
(Males or Females) Who commonly experiences OA more often after 50 y/o?
Women
What is the leading cause of disability in the elderly?
Knee OA
Signs and symptoms
- pain
- swelling
- decreased ROM
- bony deformity
OA
What medications are commonly used for OA?
- NSAIDS
- corticosteroid injections
- oral analgesics
What is Ankylosing spondylitis?
Progressive inflammatory disorder that initially affects the axial skeleton
Where in the body does ankylosing spondylitis initially affect?
axial skeleton
When is the initial onset of ankylosing spondylitis?
before 40 y/o
What are commonly the first symptoms of ankylosing spondylitis?
- mid/low back pain
- morning stiffness
- sacroiliitis
Are males or females more commonly affected by ankylosing spondylitis?
Males
What medications are commonly used for ankylosing spondylitis?
- NSAIDS
- corticosteroids
- cytotoxic drugs
- TNF inhibitors
- immunosuppresion drugs
What do cytotoxic drugs do?
Block cell growth
What is gout?
Genetic disorder of purine metabolism characterized by elevated serum uric acid (hyperuricemia) that changes into crystals and deposits into joints and other tissues
Where is gout commonly seen?
- Knees
- Great toe
What medications are used for gout?
- NSAIDS
- COX-2 inhibitors
- colchicine
- corticosteroids
- adrenocorticotropic hormone (ACTH)
- allopurinol
- proenecid
- sulfinpyrazone
What is psoriatic arthritis?
Chronic, erosive inflammatory disorder associated with psoriasis
What lab value can be used to rule in ankylosing spondylitis?
HLA-B27 antigen
What tests are used to look for gout?
Samples inspecting monosodium urate crystals in synovial fluid and connective tissues
Are males or females affected more by psoriatic arthritis?
Equally affected
What medications are commonly used to treat psoriatic arthritis?
- NSAIDS
- corticosteroids
- acetaminophen
- DMARDs
- biological response modifiers (BRMs)
What is rheumatoid arthritis?
Chronic systemic autoimmune disorder
–> Individuals produce antibodies to their own immunogloulins, such as rheumatoid factor and ACPA.
thought to have genetic etiology
Commonly characterized by periods of exacerbation and remission
Are men or women affected more by RA?
women
When is the avg onset of RA?
40-60 y/o
Signs and symptoms
- periods of exacerbation and remission
- bilateral and symmetrical synovial joint involvement
- inflammation
- weight loss
- fever
- extreme fatigue
RA
What joints are commonly affected by RA?
hands, feet, cx spine
When is the onset of juvenile RA (JRA)?
before 16 y/o
Remission in 75% of cases
What diagnostic tests are used to diagnose RA?
- tadiographs
- increased WBCs
- increased ESR
- anemia
- increased Rheumatoid factor
What medications are used for RA?
- DMARDs
- NSAIDS
- corticosteroids
- immuosuppresive agents
Are men or women more commonly affected by osteoporosis?
women
What are common sites of fx caused by osteoporosis?
- Thoracic and lumbar spine
- femoral neck
- proximal humerus
- proximal tibia
- pelvis
- distal radius
What primarily causes primary or postmenopausal osteoporosis?
decreased estrogen production
What causes senile Osteoporosis?
Decreased bone cell activity secondary to genetics or acquired abnormalities
What medications are used for osteoporosis?
- calcium
- vitamin D
- estrogen
- calcitonin
- biophosphonates
What diagnostic tests are used to detect osteoporosis?
CT scan
What diagnosis is characterized by decalcification of bones due to vitamin D deficiency?
Osteomalacia
Signs and symptoms
- severe pain
- Fx
- weakness
- deformities
osteomalacia
What medications are used to treat osteomalacia?
- vitamin D
- calcium
What diagnostic tests are used to detect osteomalacia?
- bone scans
- urinalysis and blood work
- bone biopsy
- plain films
What is osteomyelitis caused by?
infection
commonly staphylococcus aureus
What populations commonly experience osteomyelitis?
- Children
- immunosuppressed adults
- males
What diagnosis is characterized by trigger points?
myofascial pain syndrome
What are the histological characteristics of tendinosis/tendinopathy?
- hypercellularity
- hypervascularity
- no indication of inflammatory infiltrates
- loose collagen fibers
What medications are used for tendinosis/tendinopathy and bursitis?
- NSAIDs
- Acetaminophen
- steroid injections
What is the common cause of myositis ossificans?
Direct trauma resulting in hematoma and calcification within the muscle belly
Can also be caused by early mobilization and stretching w/ aggressive PT following trauma to the muscle
What are the common locations to experience myositis ossificans?
- quads
- brachialis
- biceps
When is surgery warranted to treat myositis ossificans?
- Only in patients with hereditary myositis ossificans
- after maturation of the lesion (6-24 months)
- when lesions mechanically interfere with joint movement or cause nerve impingement
What diagnosis is commonly referred to as reflex sympathetic dystrophy (RSD)?
CRPS
Thought to be related to trauma or precipitating event
What does CRPS result in?
Dysfunction of sympathetic nervous system to include pain, circulation, and vasomotor disturbances
What triggers CRPS I?
Tissue injury
Diagnosis
Dysfunction of sympathetic nervous system including pain, circulation, and vasomotor disturbances WITHOUT nerve injury
CRPS I
What is the difference between CRPS I and II?
CRPS II involves a nerve injury
What medications can be used to treat CRPS?
- antiseizure drugs
- antidepressants
- corticosteroids
- opioids
- topical drugs
What are the long term results of CRPS?
- atrophy and weakness
- skin changes
- decreased bone density
- decreased proprioception
- contractures
What clinical diagnostic tests are used to diagnose CRPS?
None
What is the common name for Osteitis Deformans?
Paget’s disease
What is Paget’s disease?
Metaobolic bone disease involving abnormal osteoblastic and osteoclastic activity
What does Paget’s disease commonly result in?
- spinal stenosis
- facet arthropathy
- possible spinal Fx
What is the presentation of torticollis?
SB toward the affected side
+
ROT away from the affected side
Most traumatic GH instability occurs in what direction of dislocation?
anteroinferior
(true/false) Posterior dislocations of the GH joint are common
FALSE
What is a hill-sachs lesion?
compression Fx of posterior humeral head
What is a bankart lesion?
avulation of anteroinferior capsule and glenoid labrum
(true or false) Immoilization for a greater tuberosity fracture is not needed
True
With what diagnoses is adhesive capsulitis most common?
DM and thyroid disease
What is de-quervain’s synovitis?
inflammation/degeneration of extensor pollicis brevis and aductor pollicis longus tendons
located in first dorsal compartment
What causes de-quervains synovitis?
Repetitive microtrauma or complication of swelling during pregnancy
What action can relieve symptoms of carpal tunnel?
Shaking hands
What interventions are allowed to treat de-quervain’s synovitis?
- heat
- microwave diathermy
- IFC
What is the most common wrist fracture?
Colle’s
How long are colle’s fractures immobilized for?
5-8 weeks
What are complications of a colle’s fracture?
Median nerve impingement caused by excessive edema
What is the most common carpal to be fractured?
Scaphoid
What wrist pathology has a “garden spade” deformity?
smith’s Fx
How long are carpals immoilized after a scaphoid fx?
4-8 wks
Are males or females more likely to experience a Dupuytren’s Fx?
Males
What special tests can be positive in the presence of ITB tightness?
Noble compression test
Ober’s test
What is coxa vara usually a result of?
defect in femoral head ossification
Most people with trochanteric bursitis also have what?
RA
What is the common cause for coxa vara and coxa valga?
Necrosis of femoral head occurring from septic arthritis
What degree of hip ER is indicative of possible piriformis syndrome?
< 60 degrees
When does the piriformis become an interal rotator and abductor of the hip?
90 degrees of hip FLX
Signs and symptoms
- acute or gradual onset of pain in the groin
- pathology with one+ of the following: adductors, iliopsoas, inguinal, pubic
sports hernia
What are the 6 P’s of acute compartment syndrome?
- pain
- pallor
- paresis
- parasthesia
- palpable tenderness
- pulselessness
(true/false) Acute compartment syndrome is a medical emergency requiring an emergent fasciotomy
true
What is the cause of acute compartment syndrome?
direct trauma and/or fracture
What is the most common LE compartment to experience chronic exertional compartment syndrome?
anterior
results in anterolateral pain and possible paresthesia
(true/false) Medial ankle ligaments are commonly sprained
FALSE
lateral is more common
What is medial tibial stress syndrome?
Overuse injury of the posterior tibialis and/or medial soleus resulting in periosteal inflammation at muscle attachment sites
What are the criteria for diagnosis of carpal tunnel syndrome?
- age > 45 y/o
- shaking hands relieves symptoms
- sensory loss in thumb
- wrist ration index > .67
- CTQ-SSS score is > 1/9
What is dupuytrens contracture?
Contracture caused by palmar fascia affecting the MCPs and PIP joints
What digits are commonly affected by dupuytren’s contracture in those with diabetes?
3rd and 4th digits
What digits are commonly affected by dupuytren’s contracture in those without diabetes?
4th and 5th digits
Describe boutionniere deformity.
Rupture of central tendinous slip of the extensor hood – MCP EXT, PIP FLX, DIP EXT
When commonly causes boutionniere deformity?
- trauma
- RA w/ central extensor tendon degeneration
Describe swan neck deformity.
MCP FLX, PIP EXT, DIP FLX
Results from contracture of intrinsic mm with dorsal suluxation of lateral extensor tendons
When does swan neck deformity commonly occur?
- Trauma
- RA w/ degeneration of lateral extensor tendons
Describe Ape hand deformity.
Muscle wasting of thenar eminence - parallel to 2nd digit
Describe mallet finger.
DIP FLX due to avulsion of extensor tendon
Caused by trauma forcing the digit into FLX
What is another name for Flexor digitorum profundus tendon rupture?
Jersey finger
Describe jersey finger.
DIP hyperEXT
Caused by excessive hyperEXT w/ maximal finger FLX contraction
What digit commonly experiences jersey finger?
Ring finger
Describe gamekeeper’s thumb
Sprain/rupture of UCL in the 1st digit MCP joint – medial instability of the thumb
Describe boxer’s Fx?
5th metacarpal Fx (at the neck)
casted for 2-4 wks
Femoroacetabular impingement (FAI) is frequently associated with what other pathology?
Labral tear
What combined movements cause the unhappy triad?
ACL, MCL, medial meniscus injury
- Valgus
- FLX
- ER
When foot is planted
What combination of movements can cause Meniscal injury?
- ROT
- FLX
- compression
When can NMES be used for ACL sprains?
6-8 weeks after ACL reconstruction
When can concentric and eccentric exercises start after ACL reconstruction?
4-6 wks for up to 10 months
ACL injury prevention programs should be stressed with what population due to a higher risk of experiencing ACL injury?
Females 12-25 y/o
involved in high-risk sports
What are the criteria used for diagnosis of meniscal tear?
- twisting injury
- tearing sensation
- delated effusion
- Hx of catching/locking
- pain with HyperEXT
- pain with max. FLX
- (+) McMurrays
- (+) Thessaly’s
- joint line tenderness
What is PFPS a result of?
Elevated patellofemoral joint loading caused by one or more of the following:
1. trauma
2. biomechanics
3. muscle tightness
4. muscle weakness
Can also be assoc. with patellar tendinopathy and/or chondromalacia patellae
What is another name for “Fat pad syndrome of the knee”?
Hoffa’s syndrome
What is jumper’s knee?
Patellar tendinosis/tendinopathy
degenerative condition of patellar tendon; commonly deep aspect
What commonly causes pes anserine bursitis?
- Overuse
- contusion
What criteria should be used for diagnosis of PFPS?
- retropatellar or peripatellar pain
- reproduction of pain with squatting, stairs, prolonged sitting, or other loading activities
- exclusion of other possible dx
What femoral condyle is commonly fractured?
Medial
What are the Ottawa Knee rules?
- age > 55 y/o
- isolated patellar tenderness
- TTP of fibular head
- Unable to perform Knee FLX > 90 degrees
- Unable to WB immediately after injury and in ED
What are the Ottawa knee and ankle rules used for?
To rule-in the need for XR series
What is the common MOI for tibial plateau Fx?
combination of valgus and compression during knee FLX
What is the common MOI for epiphyseal plate Fx?
WB torsional stress
Most stress Fx occur in what LE bone?
Tibia
What is a grade I lateral ankle sprain?
- no loss of function
- minimal tearing of ATFL
- minimal tearing of calcaneofiular ligaments