MSK Flashcards
Well-Defined Lytic Lesions
- Mets (RCC, Thyroid)
- Multiple myeloma/Plasmacytoma
- GCT
- Enchondroma (hands/feet)
- Clear cell chondrosarcoma
- Desmoid
- FD
- Brown tumor
- Hemophiliac pseudotumor
- Subacute OM (Brodie’s abscess)
- Osteoblastoma
Only in Pts < 30yo
- ABC
- SBC
- Non-ossifying fibroma
- Chondroblastoma
- Chondromyxoid fibroma
- EG
Automatics Based on Age
< 30yo
- EG - Infection
> 40yo
- Mets - Multiple myeloma - Infection
Multiple Lesions
- FD
- EG
- Enchondromas
- Mets/Myeloma
- Brown tumors
- Infection
Lesions w/o Pain
- FD
- Enchondroma
- NOF
- UBC
Diffuse Periostitis (Adults)
- Hypertrophic osteoarthropathy
- Venous stasis
- Hypervitaminosis A
- Thyroid acropachy
Lesions w/ Fluid-Fluid Levels
- ABC
- GCT
- Chondroblastoma
- Osteoblastoma
- Telangiectatic osteosarcoma
Madelung Deformity
- Trauma (Salter-Harris)
- Infection
- Turner’s syndrome
- Mucopolysaccharidoses (Morquio)
Enlarged Bones/Focal Gigantism
- Paget’s
- NF1
- Acromegaly
- Klippel-Trenaunay-Weber
- Macrodystrophia lipomatosis
- Fibrolipomatous hamartoma
- Ollier’s/Maffucci’s
- JIA/Hemophilia (epiphyseal overgrowth)
Acro-Osteolysis
Distal Predominant
- Scleroderma
- Psoriatic arthritis
- HyperPTH
- Thermal injury
- Pyknodysostosis
Band-Like
- HyperPTH
- PVC exposure
- Hadju-Cheney syndrome
Lucent Metaphyseal Bands
- Leukemia/Lymphoma
- Neonatal syphilis (Wimberger’s sign)
- Neuroblastoma mets
- Early stage rickets/scurvy
- Growth arrest lines
Dense Metaphyseal Bands
- Growth arrest/stress lines
- Chronic anemia (SCD, Thalassemia)
- Lead poisoning
- Chemotherapy
- Osteopathia striata
- Osteopetrosis
- Healing stages rickets/scurvy
- Hypothyroidism
- HypoPTH
Bone Bowing
- Paget’s
- Osteogenesis imperfecta
- Osteomalacia/Rickets
- FD
- Growth plate injury (Salter-Harris)
- NF1
Posterior Element Lesions
- TB
- OO/Osteoblastoma
- ABC
- Mets
Vertebral Body Lesions
- Hemangioma
- Mets/Myeloma
- OO/Osteoblastoma
- GCT
- EG
- Chordoma
Ivory Vertebrae
- Lymphoma
- Mets
- Paget’s
- Chronic OM
- Osteosarcoma
Bullet-Shaped Vertebrae
- Achondroplasia
- Hypothyroidism
- Down syndrome
- Mucopolysaccharidoses
- Morquio’s –> middle
- Hurler’s —> inferior
Iliac Wing Lesions
- FD
- SBC
- Brown tumor
- GCT
- Chondrosarcoma
- Ewing sarcoma
- Mets/Myeloma
Soft Tissue Calcification
- Metastatic
- HyperPTH
- Renal osteodystrophy
- Dystrophic
- Trauma
- Calcinosis
- Scleroderma
- Dermatomyositis
- Tumoral calcinosis
- SLE
Periarticular Soft Tissue Calcification
- Hydroxyapatite deposition
- Gout
- Scleroderma/SLE/Dermatomyositis
- Hypercalcemia
- HyperPTH
- Renal failure
- Hypervitaminosis D
Rib Lesions
- FD
- ABC
- Mets/Myeloma
- EG
- Enchondroma
- Chondrosarcoma
- Ewing’s sarcoma (Askin)
Expansile Lytic Lesions
- Mets (thyroid, RCC)
- Multiple myeloma (ribs)
- ABC
- GCT
- Brown tumor
- Enchondroma
- NOF
- Fibrous dysplasia
- SBC
- Hemophiliac pseudotumor
Epiphyseal Lytic Lesion (< 30yo)
- GCT
- ABC
- Chondroblastoma
- EG
- Infection (Brodie’s abscess)
Epiphyseal Lytic Lesion (> 40yo)
- GCT
- Infection
- Mets/Myeloma
- Geode
- Clear cell chondrosarcoma
Lesions w/ Sequestrum
- OM
- EG
- Fibrosarcoma
- Lymphoma
- Mets
- Osteoid osteoma (pseudosequestrum)
Gracile Bones (Overtubulation)
1) NF1
2) JRA
3) OI
4) Immobilization or Paralysis
- Congenital CNS lesions
- Birth palsies
5) Muscular dystrophy
Epiphyseal Equivalents
- Greater trochanter
- Patella
- Carpal bones
- Calcaneus
- Subarticular Flat bones
- Acetabulum
- Glenoid of scapula
- Around SI jts
Ribbon Ribs
"HORNS" H - HyperPTH O- OI R - RA N - NF1 S - Scleroderma
Mets
1) Lytic
- Lung
- Kidney
- Breast
- Thyroid
- GI
- Neuroblastoma
2) Blastic
- Prostate
- Carcinoid
- Medulloblastoma
3) Mixed
- Lung
- Breast
- GI
4) Lysis w/ Blowout
- Thyroid
- RCC
Dactylitis
1) SCD
2) Psoriatic arthritis
3) TB
Avascular Necrosis
“ASEPTIC”
- Anemia from SCD
- Steroid use, SLE, Scleroderma
- Ethanol
- Pancreatitis
- Trauma
- Infection/Idiopathic (Blount, Keinbock, Panner’s, L-C-P)
- Caisson’s dz
Finger Masses
1) Bone Centered (Non-Aggressive)
- Enchondroma
- Epidermoid inclusion cyst
- BPOP
- Juxtacortical chondroma
- Osteochondroma
- Subungual exostosis
2) Bone Centered (Aggressive)
- Mets
- Myeloma
- Infection
3) Soft Tissue Centered
- Giant cell tumor of tendon sheath
- Lipoma
- Ganglion cyst
- Glomus tumor
- PNST
Non-Specific Soft Tissue Mass (XR)
1) Lipoma
2) PNST
3) Hematoma
4) Epidermal lesion
5) Sarcoma
Erosion of Distal Clavicle
1) Bilateral
- RA
- HyperPTH
- Cleidocranial dysplasia
- Gorlin disease/Vanishing bone disease
2) Unilateral
- Septic arthritis
- Post-traumatic osteolysis
- Mets/Myeloma
High Riding Humerus
1) Rotator cuff tear
2) RA
3) CPPD
Erlenmeyer Flask Deformity
1) Gaucher’s dz
2) Osteopetrosis
3) Hemoglobinopathies (Thalassemia, SCD)
4) FD
5) Multiple hereditary exostoses
6) Enchondromatosis
Diffuse Osteosclerosis
1) Mets - breast, prostate
2) Renal osteodystrophy
3) Osteopetrosis
4) Mastocytosis
5) Myelofibrosis
6) Pyknodysostosis
7) SCA
8) Paget’s
9) Lymphoma
10) Fluorosis
Sacral Tumors
1) Chordoma
2) Chondrosarcoma
3) GCT
4) Mets/Myeloma
5) Tarlov cyst
6) Sacrococcygeal teratoma (paeds)
Epiphyseal Overgrowth
1) Hemophilia
2) JIA
3) Paralysis
4) TB arthritis
Coarse Trabeculation
1) Osteopenia
2) Hemangioma
3) Paget’s
4) Thalassemia
5) Plasmacytoma (mini-brain appearance)
Diffuse Osteopenia
1) Osteoporosis
2) Multiple myeloma
3) Leukemia
4) Thalassemia
5) Gaucher’s
Regional Osteoporosis
1) Disuse
2) AVN
3) Periarticular from Arthritis
- RA, septic arthritis, SLE, RSD
4) AVN
5) Transient osteoporosis of the hip
6) Regional migratory osteoporosis
7) Ill-defined lytic lesions
Cortical Striation/Tunneling (Rapid Bone Turnover)
1) HyperPTH
2) Renal Osteodystrophy
3) Osteomalacia
4) Disuse
5) Paget’s
Multifocal Sclerotic Lesions
1) Blastic mets
2) Osteopoikilosis
3) TS
4) Fluorosis
5) Mastocytosis
6) Paget’s
Ill-Defined Lytic Lesions
1) Mets/Myeloma
2) Lymphoma/Leukemia
3) Acute OM
4) EG
5) Hemangioma
6) Ewing’s
7) Telangiectatic osteosarcoma
8) Fibrosarcoma
Multiple Lytic Lesions
1) Mets/Myeloma
2) OM
3) FD
4) Brown tumors
5) EG
6) Lymphoma/Leukemia
7) Enchondromas
Intertrochanteric Tumor
1) Lipoma
2) Liposclerosing myxofibrous tumor
3) FD
4) SBC
Well-Defined Sclerotic Lesion
1) Mets
2) Bone island
3) Osteoid osteoma
4) Osteoblastoma
5) Mature bone infarct
6) Enchondroma
7) FD
8) Healing stress fracture
9) Involuted NOF
Ill-Defined Sclerotic Lesion
1) Met
2) Immature bone infarct
3) Osteosarcoma
4) Chondrosarcoma
5) Stress #
6) Paget’s
7) Chronic OM
Focal Periostitis/Cortical Hyperostosis
1) Stress #
2) OM
3) Melorrheostosis
4) Myositis ossificans
5) Tumor
- Osteoma
- Osteoid osteoma
- Osteoblastoma
- Chondroblastoma
- Parosteal osteosarcoma
Diffuse Periostitis (Kids)
1) Physiologic
2) Caffey’s dz
3) NAI
4) Prostaglandin Rx
5) Malignancy
6) Congenital syphilis
Heterotopic Ossification
1) Trauma
2) Neurologic injury (TBI, Stroke, Spinal cord injury)
3) Burns
4) Myositis ossificans progressiva
Extensive Callous Formation
1) Steroids
- Exogenous
- Cushing’s dz
2) OI
3) Infection
4) Trauma
5) Paralysis/Neuromuscular disorder
Cortically-Based Lesions
1) Cortical desmoid
2) Osteoid osteoma
3) NOF
4) Parosteal osteosarcoma
5) Cortical FD
6) Adamantinoma
7) Ossifying fibroma
Short Metacarpal/Metatarsal
1) Idiopathic
2) JIA
3) Turner’s
4) Muccopolysacharidoses
5) Hypoparathyroidism
6) Trauma
7) SCD
Diaphyseal Bone Lesion
“FEMALE”
- FD
- EG
- Met
- Adamantinoma/Ossifying fibroma
- Lymphoma/Leukemia
- Ewing’s
Coxa Magna/Coxa Breva/Coxa Plana
1) Trauma
2) Prior Legg-Calve-Perthes
3) DDH
Subchondral Cysts
1) Degenerative jt dz
2) CPPD
3) RA
4) Ischemia/AVN
Acetabular Protrusion
1) RA
2) JIA
3) Trauma
4) Infection
5) Osteomalacia
6) Paget’s
7) AS
Permeative Lesion
1) OM
2) Small round blue cell tumors
- Ewing’s
- Lymphoma/Leukemia
- Neuroblastoma
- Multiple myeloma
3) EG
Premature Closure of Physis
1) Truma
2) JIA
3) Infection
4) Hemophilia
5) Accelerated Skeletal Maturation
- McCune-Albright
- Hyperthyroidism
Well-Formed Bone Spurs
1) Degenerative enthesopathy
2) DISH
3) Acromegaly
Poorly-Defined Bone Spurs
1) Psoriatic arthritis
3) Reactive arthritis
4) Avulsion injury
5) AS
Tenosynovitis
1) Post-traumatic
2) Overuse
3) CTD (RA, SLE)
4) Infection
Monoarticular Arthritis
1) Trauma
2) Septic arthritis
3) PVNS
4) Synovial chondromatosis
5) Crystal Arthritides
- Gout
- CPPD
- Calcium hydroxyapatite deposition dz
Purely Erosive Arthritis
1) RA
2) Septic (acute)
3) TB (indolent)
Erosive & Proliferative Arthritis
1) Psoriatic
2) Reactive
3) AS
4) Erosive OA
Arthritis w/ Preserved Jt Space
1) Gout
2) TB (indolent course)
3) Juvenile chronic arthritis
4) Hemophilia
5) Amyloidosis
6) Synovial chondromatosis
7) SLE, Jaccoud’s
8) Reactive Synovitis - Infection, IBD, Neoplasms
Accelerated OA
1) Trauma
2) Infection
3) CPPD
4) Hemochromatosis
5) Acromegaly
6) Articular dysplasia
Calcified Intra-Articular Loose Body
1) Synovial osteochondromatosis
2) Detached osteophyte
3) Acute osteochondral #
4) Unstable OCD fragment
Non-Calcified Intra-Articular Loose Body
1) Synovial chondromatosis
2) Rice body (RA, TB)
3) Lipoma arborescens
DDx Joint Effusion
1) Trauma
2) Infection
3) Seronegative spondyloarthropathy
4) RA/JIA
5) Tarsal/Carpal coalition
6) Effusion Mimics
- Amyloid
- PVNS
- Hemophilia
Olecranon Bursitis
1) Overuse, Dialysis
2) Trauma
3) Infection
4) RA
5) Gout
6) CPPD
Ulnar Deviation of MCPs
1) RA
2) SLE
3) Jaccoud’s arthropathy
Radial Deviation of MCPs
JIA
Hooked Osteophytes
1) CPPD (2-3 MCPs)
2) Hemochromatosis (diffuse)
Osteochondral Lesion
1) Trauma
2) Subchondral insufficiency #
3) AVN collapse
4) OCD
5) OA
Sacroiliitis
1) AS
2) HyperPTH
3) Septic arthritis
4) Reactive arthritis
5) Psoriatic arthritis
6) Enteropathic arthropathy
Arthropathy w/ Soft Tissue Mass
1) Gout
2) Amyloidosis (no blooming, low T1/T2)
3) PVNS (blooming, low T1/T2)
4) Hemophilia (bloom, low T1/T2, wide physes)
Amyloidosis vs. PVNS
Osteopenia in amyloidosis
PVNS vs. Giant Cell Tumor of Tendon Sheath
GCTTS located in soft tissue near jt
Periarticular Soft Tissue Calcification
1) Hydroxyapatite deposition
2) Gout
3) Scleroderma
4) Tumoral Calcinosis
- HyperPTH
- Renal failure
- Hypervitaminosis D
- Sarcoidosis
Soft Tissue Calcification
1) Metastatic
- HyperPTH
- Renal osteodystrophy
2) Scleroderma
3) Dermatomyositis/Polymyositis
4) SLE
5) Dystrophic (trauma)
Chondrocalcinosis
1) CPPD
2) OA
3) Gout
4) HyperPTH
5) Hemochromatosis
Spondylolisthesis
1) Spondylolysis
2) Facet degeneration
3) Degenerative disc dz
4) trauma
5) Ligamentous Laxity
- Marfan’s
- Ehlers-Danlos
Atlantoaxial Subluxation
1) Trauma
2) Arthritis
- RA
- CPPD
3) Congenital
- Down
- Morquio’s
- Congenital hypoplasia of dens/ Os odontoideum
4) Ligamentous Laxity
- Marfan’s
- Ehlers-Danlos
5) Adjacent infection (tonsilitis, pharyngitis)
Paravertebral Ossification
1) Asymmetric
- Psoriatic arthritis
- Reactive arthritis
2) Symmetric
- AS
- Enteropathic arthropathy
3) DISH (anterior)
4) TB (focal mass)
Disc Calcification
1) Degenerative disc dz
2) CPPD
3) AS
4) Surgical fusion
Enlarged Vertebrae
1) Paget’s
2) ABC
3) Acromegaly
Posterior Scalloping of Vertebrae
1) Inc Spinal Pressure
- Neoplasm (lipoma, ependymoma, schwannoma)
- Syrinx
- Long standing hydro
2) Dural Ectasia
- NF1
- Marfan’s
- Ehlers-Danlos
3) Achondroplasia
4) Acromegaly
Anterior Scalloping of Vertebrae
1) Aortic aneurysm
2) LNs
3) TB
Absent Pedicle
1) Met
2) ABC
3) Congenital absence (contralateral hypertrophy)
Dense Pedicle
1) Osteoblastic met
2) Osteoblastoma
3) Congenital absence of contralateral pedicle
Dense Vertebral Endplates
1) Degenerative disc dz
2) Renal Osteodrystrophy
3) Osteopetrosis
Increased Interpedicular Distance
1) Trauma
2) Syrinx
3) Intraspinal tumor
4) Dysraphism
5) AVM
Gibbus Deformity
1) Congenital (achondroplasia)
2) TB (Pott’s dz)
3) Fracture
4) Vertebra plana
Expansile Sternal Lesion
“MAC”
Mets/Myeloma
ABC
Chondrosarcoma
Floating Teeth
1) EG
2) Lymphoma/Leukemia
3) Periapical abscess
4) 1ry mandibular tumor
Focal Marrow Edema
1) Trauma (contusion, stress #)
2) Osteoid osteoma
3) AVN
4) Transient regional osteoporosis
5) Infection
6) Other neoplasm
Cyst Like Masses (Low T1, High T2)
1) Hematoma
2) ABscess
3) Bursa
4) Synovial cyst
5) Ganglion cyst
6) Myxoid Tumors
- Myxoma
- Myxoid liposarcoma
- MFH
- Chondrosarcoma
Soft Tissue Neoplasm
1) Lipomatous
2) Sarcoma (MFH, Synovial)
3) Angiomatous
4) Neurogenic
5) Fibromatosis
6) PVNS
Bilateral Tendon Tears
1) Steroid use
2) Renal failure
3) DM
4) CTD (SLE, RA)
Cortical Based Tumors
1) Mets
2) Myeloma
3) NOF
4) Osteoid Osteoma
5) ABC
6) Chondromyxoid Fibroma
7) Adamantinoma
8) EG
Malignant Transformation of Bone Tumors
1) FD –> Osteosarcoma, Fibrosarcoma
2) Paget’s –> Osteosarcoma
3) OM w/ Draining Sinus –> SCC
4) Radiation –> OSA, Chondrosarcoma, MFH
5) Bone Infarct –> Fibrosarcoma, MFH
6) Ollier’s/Maffucci –> Chondrosarcoma
7) Hereditary Exostosis –> Chondrosarcoma
Radial Hypoplasia
1) VACTERL
2) Holt-Oram
3) Fanconi’s anemia
Widened Pubic Symphysis
1) Congenital
- Bladder exstrophy
- Cleidocranial dysplasia
- GU or anorectal malformations
2) Bone Resorption/Destruction
- Pregnancy
- Osteitis pubis
- Infection
- Mets
- HyperPTH
Platyspondyly
1) Diffuse
- Dwarf syndromes
- OI
- Morquio’s
2) Solitary
- Leukemia
- EG
- Mets/Myeloma
SCD
Acquired Lucent Ribs
1) Acromegaly
2) Cushing’s dz
3) Scurvy