Movement Flashcards
Fissure that separates the flocculonodular lobe from the corpus cerebelli
Posterolateral fissure
Fissure that separates the anterior lobe from the corpus cerebelli
Primary fissure
Two types of inhibitory neurons consisting the outermost molecular layer of the cerebellum
stellate cells and basket cells
Neurotransmitter utilized by the mossy fibers
Aspartate
Receptive part of the basal ganglia
Putamen
The condition is characterized by an inability to sustain the fingers and toes, tongue or any other part of the body in one position.
Athetosis
T/F: Bilateral ballismus is infrequent and usually asymmetrical.
True
Gene which accounts for 50% of early-onset inherited PD.
Park-2
What percentage of PD patients will not present with characteristic tremor?
25%
PD drug that causes urine discoloration, diarrhea and increased dyskinesias
Entacapone
In primary orthostatic tremor, electromyographic recordings demonstrate rhythmic cocontraction of what muscles?
Gastrocnemius and anterior tibialis muscles
A lesion in what cerebellar nucleus causes an ipsilateral tremor of ataxic type.
Nucleus interpositus or dentate nucleus
This movement disorder was incorrectly been referred as negative tremor.
Asterixis
Triad of AD, choreoathetosis and dementia
Huntington disease
Rigid form of Huntington disease
Westphal (HDL2 variant)
Presents with atrophy of the cerebellum, cerebellar peduncles, pons (hot-cross-bun sign)
Multiple system atrophy
Most important microscopic feature of progressive supranuclear palsy
Globose tangles
Concomitant administration of peripheral dopa decarboxylase inhibitor such as carbidopa may reduce the daily requirements of levodopa by how many percent?
Approximately 75%
Type of Monoamine oxidase that metabolizes dopamine selectively
Monoamine oxidase B
T/F: Acetylcholine-blocking agents may improve the tremor and rigidity of parkinsonism but have little effect on bradykinesia.
True
Movement disorder with highest risk for depression with suicide
Huntington disease
Drug used for the treatment of PD which can produce livido reticularis and other dermatologic adverse effects
Amantadine
Ballismus is a clinical condition that primarily results from injury to what structure?
Subthalamic nucleus
T/F: Patients with Huntington’s disease before the age 20 are more likely to have hypokinesia and rigidity at an early stage.
True