Motor Systems and Associated Structures Flashcards

1
Q

where is lamina 9 of rexed’s laminae found and what does it contain?

A

ventral horn of spinal cord
cell bodies of lower motor neuron cell bodies

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2
Q

what neuron fibre type carries motor information to skeletal muscle

A

A alpha

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3
Q

are A alpha fibres myelinated

A

yes

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4
Q

what type of muscle fibre supplies muscle spindle

A

a-gamma

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5
Q

what type of neuron fibre is unmyelinated

A

C

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6
Q

how does the size of CNS synapse compare to a neuromuscular junction

A

neuromuscular junction much larger (up to 50x bigger)

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7
Q

what type of neurotransmitter is found in NMJ

A

acetylcholine

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8
Q

how muscle fibres does a NMJ supply

A

one

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9
Q

function of upper motor neurons

A

control firing pattern of lower motor neurons

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10
Q

what is the simplest motor pathway called

A

corticospinal pathway

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11
Q

function of corticospinal pathway

A

control of voluntary and precise movement

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12
Q

how many neurons in corticospinal pathway

A

2 (upper and lower)

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13
Q

is the corticospinal pathway contralateral or ipsilateral

A

contralateral

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14
Q

corticospinal pathway is aka

A

pyramidal tract/pathway

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15
Q

what five locations can upper motor neuron cell bodies be found

A

primary motor cortex (majority)
pre-motor cortex
supplementary motor cortex
cingulate motor cortex
somatic sensory cortex

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16
Q

pathway of an upper motor neuron

A
  1. cortical grey matter (e.g. primary motor cortex)
  2. corona radiata
  3. internal capsule
  4. crus cerebri of midbrain
  5. pontine corticospinal tracts
  6. pyramid of medulla
  7. lateral/ventral corticospinal tracts of spinal cord
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17
Q

where is the crus cerebri found

A

anterior lateral aspects midbrain (R and L)
thick section of white matter (note - may be stained dark)

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18
Q

what feature can help identify the pons on a stained cross section

A

horizontal darker lines

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19
Q

where are the pontine corticospinal tracts found

A

medial and anterior pons

20
Q

where are pyramids of the medulla found

A

triangular shapes on anterior medial medulla

21
Q

where do neurons decussate in the corticospinal pathway

A

75-90% in decussation of the pyramids
10-25% in spinal cord at level of lower motor neuron

22
Q

the neurons which decussate in the medulla form which pathway

A

lateral corticospinal pathway

23
Q

the neurons which do not decussate in the corticospinal pathway form which pathway

A

ventral corticospinal pathway

24
Q

where does the ventral corticospinal neurons decussate

A

ventral white commissure

25
Q

an overactive reflex arc leads to

A

spasticity

26
Q

what pathway controls motor innervation to the cranial nerves

A

corticobulbar pathway

27
Q

where are the lower motor neurons located that are controlled by the upper motor neurons found in the corticobulbar pathway

A

cranial nerve nuclei of the brain stem

28
Q

what are the 4 extra-pyramidal motor pathways

A

rubrospinal tract
vestibulospinal tract
tectospinal tract
reticulospinal tract

29
Q

is the rubrospinal tract contralateral or ipsilateral

A

contra

30
Q

is the vestibulospinal tract contralateral or ipsilateral

A

ipsi

31
Q

is the tectospinal tract contralateral or ipsilateral

A

contra

32
Q

is the reticulospinal tract contralateral or ipsilateral

A

ipsi

33
Q

where are the cell bodies of the rubrospinal tract found

A

red nucleus in midbrain

34
Q

where are the cell bodies of the vestibulospinal tract found

A

vestibular nuclei in pons and medulla

35
Q

where are the cell bodies of the tectospinal tract found

A

superior colliculus in midbrain

36
Q

where are the cell bodies of the reticulospinal tract found

A

reticular nuclei in brain stem

37
Q

effects of upper motor neuron loss

A

voluntary movements of affected muscles are weak
no profound muscle atrophy but may be slow wasting
spasticity (due to no inhibition to relfex acrs)
postitive babinski reflex (dorsiflexion of big toe when stroking sole of foot)

38
Q

effects of lower motor neuron loss

A

affected muscles are weak or paralysed (if all LMN are lost)
profound muscle atrophy
tendon reflexes are weak or absent
fibrillation potentials can be recorded from denervated muscle
fasciculation occurs (irregular muscle twitching)

39
Q

are the basal ganglia pyramidal or extra pyramidal

A

extra

40
Q

function of basal ganglia

A

filter out unwanted movement and approve wanted movement

41
Q

diseases caused by basal ganglia loss of function

A

parkinsons
huntingtons

42
Q

what are the six parts of the basal ganglia

A

caudate
putamen
globus pallidus external
globus pallidus internal
subthalamic nucleus
substantia nigra

43
Q

the putamen, globus pallidus external and globus pallidus internal form the

A

lentiform nucleus

44
Q

where is subthalamic nucleus found

A

superior to hypothalamus which is superior to pituitary

45
Q

where is substantia nigra found

A

midbrain just posterior to the crus cerebri