Motor Neurone Disease Flashcards
1
Q
MND
A
neuromuscular disease
2
Q
types
A
amyotrophic lateral sclerosis - UMN + LMN
primary lateral sclerosis - UMN
progressive bulbar palsy
progressive muscular atrophy
3
Q
UMN and LMN signs
A
UMN:
hyperreflexia
hypertonia
plantar reflex
LMN: fasciculations muscle wasting hyporeflexia hypotonia
4
Q
investigations
A
neurologist specialist
excluded other differential diagnoses
5
Q
classic signs
A
>40 yrs old male gradual weakness UMN/LMN signs sensory not affected cough present speech and swallowing signs
6
Q
management
A
riluzole
symptomatic
MDT
bad prognosis
7
Q
what would be seen in nerve conduction studies
A
normal motor conduction
8
Q
what muscles are spared
A
ocular
9
Q
what dementia can be seen
A
frontotemporal
10
Q
what carries the worse prognosis
A
progressive bulbar palsy
