Motor Control Flashcards
what is a tendon ?
muscle to bone
what is a ligament ?
bone to bone
where are lower motor neurons located ?
ventral spinal cord
what is a motor unit ?
composed of the motor neurone and all the muscle fibres that it innervates
what is the organization of muscles from largest to smallest ?
muscle, fascicle, myofibril, and myofilaments
what is a motor neurone pool ?
all the motor neurons that deal with the same muscle
what are the two motor neuron responses ?
phasic and tonic
what does phasic mean ?
quick bursts
what does tonic meanx ?
sustained responses
what are the two muscle spindles ?
extrafusal and intrafusal muscle fibers ?
what do extrafusal muscle fibres innervate ?
alpha motor neurons
what do intrafusal muscle fibres innervate ?
gamma motor neurons
what are extrafusal fibres used for ?
contractions
what are intrafusal fibres used for ?
messengers of contractions (tells body about change in length of muscles)
intrafusal fibres tonically activate _______ ?
1a afferent sensory neurons
what do golgi tendon organs do ?
tells us how much tension is in the muscle
golgi tendon organ receptor are attached to _____ ?
1b afferent sensory neurons
what is alpha-gamma coactivation ?
when both extra- and intrafusal fibres contract and work together
what is the difference between white and gray matter ?
white matter is myelinated and gray is not
what is the corticospinal tract ?
the primary pathway that leaves the motor cortex to innervate motor neurons in the spinal cord
what is BMI (brain machine interfaces) ?
used to help people generate movement
where is the cerebellum located ?
mini brain in the back of brain
what is the function of the cerebellum ?
maintenance of balance and posture and helps coordinate and regulate multiple functions in your body and brain
what is a cerebellar lesion ?
decomposition of movement and dysmetria
what is cerebellar disease ?
can’t balance themselves
what are symptoms of cerebellar disease ?
- wide gait
- instability of trunk
- irregular staggering steps
what are the two types of input neurons ?
mossy fibers and climbing fibers
what are mossy fibers ?
- synapse on granule cells (shorter) then on purkinje cells
what are climbing fibers ?
synapse directly on purkinje fibres (longer)
what is the basal ganglia ?
involved in regulating and planning movements
the basal ganglia receives inputs from the ______ and projects back to the cortex through the hypothalamus ______
cortex and thalamus
what are the four major interconnected nuclei found in the basal ganglia ?
- striatum
- globus pallidus
- substantia nigra
- sub thalamic nucleus
what are the two parts of the striatum ?
caudate and putamen
what are the two parts of the substantial nigra ?
pars compacta and pars reticulata
what is the order of activity in the basal ganglia ?
motor cortex -> caudate & putamen -> substantia nigra pars reticulata and globus pallidus internal … substantia nigra pars reticulata -> superior colliculus and globus pallidus internal -> thalamus
what receptors go to substantial nigra pc ?
dopamine 1 and dopamine 2 receptor
what is the indirect pathway of the basal ganglia ?
putamen -> G. pallidus external -> subthalamic nucleus
what is the direct pathway of the basal ganglia ?
putamen -> G. pallidus internal
what is parkinson’s disease ?
is a progressive, neurodegenerative disease
what is happening in the brain if you have parkinson’s ?
loss of neurons in the substantia nigra
what causes parkinson’s ?
caused by a loss of the dopaminergic neurons of the substantia nigra pars compacta
what are symptoms of Parkinson’s disease ?
- tremor at rest
- slowness of movement
- hunched over
- minimal facial expression
motor symptoms of Parkinson’s disease ?
- rigid gait
- stooped foward
- slow movement initiation
- slow shuffling steps
- hypokinesia
how to treat Parkinson’s disease ?
L-Dopa (converts to dopamine in the body)
what is a blood-brain-barrier ?
very selective layer around brain that protects the brain from infections
what is the difference between L-Dopa and dopamine ?
dopamine cannot cross the blood-brain-barrier but L-Dopa can