Morbus Parkinson/ Medikamente/ COMT-Hemmer Flashcards

1
Q

COMT-Hemmer

A
  • Comtess
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2
Q

Wirkmechanismus:

A
  • Hemmung der Catechol-O-Methyltransferase→ Dopamin erhoht
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3
Q

Anwendung

A
  • nur in Kombination mit L-Dopa
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4
Q

Nebenwirkungen:

A
  • Urinverfärbung,
  • Dyskinesien,
  • Überlkeit,
  • Diarrhö, etc.
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5
Q

Kontraindikationen:

A
  • Leberinsuffizienz,
  • Phäochromozytom,
  • malignes neuroleptisches Syndrom,
  • u.a.
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