Mood Disorders Flashcards
Definition
a region of the prefrontal cortex involved in working memory, motor planning, organisation and regulation, and implicated in many psychopathologies
Dorsolateral prefrontal cortex
Define
Interpersonal and social rhythm therapy (IPSRT)
a behavioural treatment from bipolar disorder that aims to stabilise mood by addressing disruptions in circadian rhythms (e.g., stressful life events, irregular sleep/wake times)
Definition
tendencies to perceive events in a negative manner, for example, by attending to or remembering negative information more than positive information; hypothesised to be driven by underlying negative schemas
Cognitive biases
Does the prevalence of Bipolar disorders differ by gender?
No - approximately equal in male and females
What are the major features of Premenstrual dysphoric disorder?
Mood symptoms in the week before menses
Definition
a neurosurgical treatment in which electrodes are implanted into specific brain regions
Deep brain stimulation
True or False:
Some drugs that increase dopamine levels can trigger manic symptoms in people with bipolar
True
Definition
a condition, such as major depressive disorder, whose symptoms dissipate but that tends to recur
Episodic disorder
Definition
any drug that alleviates depression; also widely used to treat anxiety disorders
Antidepressant
Definition
in Beck’s theory of depression, a person’s negative views of the self, the worlds and the future, in a reciprocal causal relationship with pessimistic assumptions (schemas) and cognitive biases such as selective abstraction
Negative triad
Definition
a drug used in treating both mania and depression in bipolar patients
Lithium
Shawna has been seeing a cognitive therapist for depression. The therapist has encouraged her to do things that will help with creating a positive experience - like getting out of bed, talking to friends, and going for a walk. This behavioral technique is called
a) interpersonal psychotherapy
b) mindfulness meditation
c) behavioral activation
d) cognitive restructuring
c) behavioral activation
Define
Mood disorders
disorders, such as depressive disorders or mania, in which there are disabling disturbances in emotion
Define
Rapid cycling
term applied to bipolar disorders if the patient has experienced at least four episodes within the past year
What is the major personality trait implicated in depression?
Neuroticism
Studies on creativity and mood disorders have shown that extreme mania __________ creative output.
a) increases
b) lowers
c) has an unknown effect on
d) has no influence on
b) lowers
Define
Psychomotor agitation
a symptom characterised by pacing, restlessness and inability to sit still
Define
Melancholic
subtype of major depressive disorder in which the individual is unable to feel better even momentarily when something good happens, regularly feels worse in the morning and awakens early and suffers a deepening of other symptoms of depression
Define
Attribution
the explanation a person has for why an event or behaviour has occurred
Definition
a form of bipolar disorder, diagnosed in those who have experienced at least one major depressive episode and at least one episode of hypomania
Bipolar II disorder
Define
Expressed emotion
hostility, criticism and emotional overinvolvement directed from other people towards the patient, usually within a family
Define
Cushing’s syndrome
an endocrine disorder usually affecting young women, produced by over secretion of cortisone and marked by mood swings, irritability, agitation and physical disfigurement
What helps explain why people with depression feel less motivated by and less engaged in positive events in their life?
Lack of activity in the striatum which is a central component of the reward system
Definition
a subtype of mood disorders in which episodes consistently occur at the same time of year; in the most common form, major depressive episodes consistently occur in the winter
Seasonal affective disorder
What is Beck’s theory of Depression?
Depression is associated with the negative triad: negative views of the self, their world, and the future
Definition
in the subcortical region of the brain, the anterior portion of the cingulate gyrus, stretching about the corpus callosum
Anterior cingulate
What different psychological treatments are used for depression?
Interpersonal psychotherapy
Cognitive-behavioral therapy
Behavioral couples therapy
Third wave cognitive therapies
Define
Monoamine oxidase inhibitors (MAOIs)
a group of antidepressant drugs that prevent the enzyme monoamine oxidase from deactivating catecholamine and indolamines
What is the goal of third wave therapies?
To assist patients to adopt a ‘decentred’ or ‘defused’ perspective by teaching them , to view thoughts as ‘mental events’ rather than accurate reflections of reality or the self
Define
Flight of ideas
a symptom of mania that involves rapid shift in conversation from one subject to another with only superficial associative connections
Define
Mindfulness-based cognitive therapy (MBCT)
a recent adaptation of cognitive therapy which draws on so-called ‘third wave’ techniques such as mindfulness meditation to help patients learn to see thoughts as harmless mental events, rather than challenge their content as in cognitive therapy
What does the atypical features specifier refer to? Which mood disorder(s) is it applicable to?
Symptoms that are unusual for depressive or manic episodes are present
Applicable to MDD and bipolar
True or False:
People with depression are less responsive than other people are to drugs that increase dopamine levels
True
Define
Tricyclic antidepressants
a group of antidepressants with molecular structure characterised by three fused rings; they interfere with the reuptake of norepinephrine and serotonin
What does the mixed features specifier refer to? Which mood disorder(s) is it applicable to?
At least three manic symptoms are present during a depressive episode, or at least three depressive symptoms are present during a manic episode
Applicable to MDD and bipolar
Define
Hypomania
an extremely elevated or irritable mood accompanied by symptoms such as increased energy and decreased need for sleep, but without the significant functional impairment associated with mania
Definition
term applied to bipolar disorders if the patient has experienced at least four episodes within the past year
Rapid cycling
Define
Episodic disorder
a condition, such as major depressive disorder, whose symptoms dissipate but that tends to recur
Definition
onset during pregnancy or within four weeks postpartum, characterising a subtype of episodes of major depressive disorder or mania
Peripartum onset
Define
Rumination
repetitive thought about why a person is experiencing negative mood
What is the DSM-5 criteria for Bipolar I?
At least one episode of mania during the course of a person’s life
Why is electroconvulsive therapy still used?
ECT is more powerful than antidepressant medication for the treatment of depression, particularly when psychotic features are present
Define
Premenstrual dysphoric disorder
a depressed, anxious, labile or irritable mood that reoccurs monthly during the luteal phase of the menstrual cycle. The symptoms are more distressing and disabling than the more commonly experienced premenstrual syndrome (PMS)
What are the major features of Cyclothymia?
Recurrent mood changes from high to low for at least two years, without hypomanic or depressive episodes
Define
Anterior cingulate
in the subcortical region of the brain, the anterior portion of the cingulate gyrus, stretching about the corpus callosum
Define
Disruptive mood dysregulation disorder
a DSM-5 disorder defined by severe temper outbursts and observably irritable mood between outbursts in youths older than age 6
Define
Behavioural couples therapy
clinical approach to depression in which couple works to improve communication and satisfaction; more likely to relieve relationship distress than individual cognitive therapy
Definition
amino acid that is the major precursor of serotonin. Experimental depletion has found that a lowered serotonin level causes temporary depressive symptoms in people with a personal or family history of depression
Tryptophan
Define
Antidepressant
any drug that alleviates depression; also widely used to treat anxiety disorders
Which has a stronger genetic influence: MDD or bipolar?
Bipolar
Definition
a group of antidepressants with molecular structure characterised by three fused rings; they interfere with the reuptake of norepinephrine and serotonin
Tricyclic antidepressants
Definition
a DSM-5 disorder defined by severe temper outbursts and observably irritable mood between outbursts in youths older than age 6
Disruptive mood dysregulation disorder
Within most psychiatric disorders, suicides are most likely to occur when a person is experiencing
a) mania.
b) comorbid depression.
c) anxiety.
d) withdrawals.
b) comorbid depression.
What are the different types of third wave cognitive therapies?
Mindfullness-based cognitive therapy
Commitment therapy
Dialectical behavior therapy (DBT)
What does the catatonia specifier refer to? Which mood disorder(s) is it applicable to?
Extreme physical immobility or excessive peculiar physical movement
Applicable to MDD and bipolar
Definition
a symptom commonly observed in major depressive disorder in which the person moves his or her limbs and body slowly
Psychomotor retardation
Define
Persistent depressive disorder
a DSM-5 disorder defined by depressive symptoms that last at least 2 years
True or False:
Major depressive episodes are usually isolated and don’t tend to recur
False
About two-thirds of individuals experience at least one more episode in their lifetime
Which of the following individuals is at greatest risk of completed suicide?
a) a 29-year-old female
b) a 17-year-old male
c) a 48-year-old female
d) a 78-year-old male
d) a 78-year-old male
Define
Reward system
system of brain structure involved in the motivation to pursue rewards. Believed to be involved in depression, mania, schizophrenia and substance use disorders
What does the mood-congruent psychotic features specifier refer to? Which mood disorder(s) is it applicable to?
Delusions or hallucinations with themes that are consistent with the mood state (e.g. guilt, disease or death themes accompanying depression)
Applicable to MDD and bipolar
Define
Bipolar II disorder
a form of bipolar disorder, diagnosed in those who have experienced at least one major depressive episode and at least one episode of hypomania
What is the problem with the causal relationship between interpersonal problems and depression?
Depressive symptoms could easily contribute to interpersonal difficulties as the person withdraws, begins to feel irritable and finds no joy when engaging with others, but these same factors may also indicate individuals at risk of developing depression.
What are the common physical symptoms of depression?
Fatigue
Low energy
Aches and pains
The Hollon et al. (2002) cognitive therapy versus antidepressants study found all of the following EXCEPT:
a) both cognitive therapy and medication helped people recover from depression more than a placebo.
b) when cognitive therapy and medications were combined, the effects were even greater than for either treatment alone.
c) cognitive therapy was more expensive than treatment with medication.
d) cognitive therapy helped protect against relapse over the long term.
c) cognitive therapy was more expensive than treatment with medication.
What are the levels of activation of the striatum in response to reward in MDD and bipolar?
MDD: Low
Bipolar: High
What does the seasonal pattern specifier refer to? Which mood disorder(s) is it applicable to?
Episodes happen regularly at a particular time of year
Applicable to MDD and bipolar
Which areas of the brain are targeted in deep brain stimulation?
Anterior cingulate
Nucleus accumbens
Definition
a group of antidepressant drugs that prevent the enzyme monoamine oxidase from deactivating catecholamine and indolamines
Monoamine oxidase inhibitors (MAOIs)
Definition
a person’s habitual manner of assigning causes to behaviours and events
Attributional style